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- Title
The Validity of Intracerebral Hemorrhage Diagnoses in the Danish Patient Registry and the Danish Stroke Registry.
- Authors
Hald, Stine Munk; Sloth, Christine Kring; Agger, Mikkel; Schelde-Olesen, Maria Therese; Højholt, Miriam; Hasle, Mette; Bogetofte, Helle; Olesrud, Ida; Binzer, Stefanie; Madsen, Charlotte; Krone, Willy; Rodríguez, Luis Alberto García; Salman, Rustam Al-Shahi; Hallas, Jesper; Gaist, David
- Abstract
Purpose: To establish the validity of intracerebral hemorrhage (ICH) diagnoses in the Danish Stroke Registry (DSR) and the Danish National Patient Registry (DNPR). Patients and Methods: Based on discharge summaries and brain imaging reports, we estimated the positive predictive value (PPV) of a first-ever diagnosis code for ICH (ICD-10, code I61) for all patients in the Region of Southern Denmark (1.2 million) during 2009– 2017 according to either DNPR or DSR. We estimated PPVs for any non-traumatic ICH (a-ICH) and spontaneous ICH (s-ICH) alone (ie, without underlying structural cause). We also calculated the sensitivity of these diagnoses in each of the registers. Finally, we classified the location of verified s-ICH. Results: A total of 3,956 patients with ICH diagnosis codes were studied (DSR only: 87; DNPR only: 1,513; both registries: 2,356). In the DSR, the PPVs were 86.5% (95% CI=85.1– 87.8) for a-ICH and 81.8% (95% CI=80.2– 83.3) for s-ICH. The PPVs in DNPR (discharge code, primary diagnostic position) were 76.2% (95% CI=74.7– 77.6) for a-ICH and 70.2% (95% CI=68.6– 71.8) for s-ICH. Sensitivity for a-ICH and s-ICH was 76.4% (95% CI=74.8– 78.0) and 78.7% (95% CI=77.1– 80.2) in DSR, and 87.3% (95% CI=86.0– 88.5) and 87.7% (95% CI=86.3– 88.9) in DNPR. The location of verified s-ICH was lobar (39%), deep (33.6%), infratentorial (13.2%), large unclassifiable (11%), isolated intraventricular (1.9%), or unclassifiable due to insufficient information (1.3%). Conclusion: The validity of a-ICH diagnoses is high in both registries. For s-ICH, PPV was higher in DSR, while sensitivity was higher in DNPR. The location of s-ICH was similar to distributions seen in other populations.
- Subjects
DENMARK; CEREBRAL hemorrhage; DIAGNOSIS; MEDICAL registries; STROKE; BRAIN imaging
- Publication
Clinical Epidemiology, 2020, Vol 12, p1313
- ISSN
1179-1349
- Publication type
Article
- DOI
10.2147/CLEP.S267583