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- Title
A New Cyclic Peptide from Betel Nut Endophytic Fungus Alternaria sp. RW-AL.
- Authors
Ruan, Wu; Ma, Qing-Yun; Guo, Jiao-Cen; Xie, Qing-Yi; Yang, Li; Dai, Hao-Fu; Wu, You-Geng; Zhao, You-Xing
- Abstract
A new cyclic peptide alternarin A (1), along with seven known compounds, alternariol (2), sulfated derivative of alternariol (3), alternariol methyl ether (4), altenuene (5), 2,5-dimethyl-7-hydroxychromone (6), diaporthein A (7), isopterocarpolone (8), were isolated from the betel nut endophytic fungus Alternaria sp. RW-AL. The structure of 1 was elucidated by 1D and 2D NMR spectra as well as HR-ESI-MS analysis. Compounds 1, 4, and 5 showed definite antibacterial activities against Staphylococcus aureus ATCC 6538 and Bacillus subtilis ATCC 6633.
- Subjects
BETEL nut; PEPTIDES; ALTERNARIA; METHYL ether; BACILLUS subtilis
- Publication
Chemistry of Natural Compounds, 2024, Vol 60, Issue 4, p693
- ISSN
0009-3130
- Publication type
Article
- DOI
10.1007/s10600-024-04413-4