We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Multifunctional enzymes related to amino acid metabolism in bacteria.
- Authors
Miyamoto, Tetsuya
- Abstract
In bacteria, d -amino acids are primarily synthesized from l -amino acids by amino acid racemases, but some bacteria use d -amino acid aminotransferases to synthesize d -amino acids. d -Amino acids are peptidoglycan components in the cell wall involved in several physiological processes, such as bacterial growth, biofilm dispersal, and peptidoglycan metabolism. Therefore, their metabolism and physiological roles have attracted increasing attention. Recently, we identified novel bacterial d -amino acid metabolic pathways, which involve amino acid racemases, with broad substrate specificity, as well as multifunctional enzymes with d -amino acid-metabolizing activity. Here, I review these multifunctional enzymes and their related d - and l -amino acid metabolic pathways in Escherichia coli and the hyperthermophile Thermotoga maritima.
- Subjects
AMINO acid metabolism; THERMOTOGA maritima; ENZYMES; BACTERIAL metabolism; RACEMASES; BACTERIAL growth; PLANT growth
- Publication
Bioscience, Biotechnology & Biochemistry, 2024, Vol 88, Issue 6, p585
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1093/bbb/zbae027