We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Cross-linked natural IntegroPectin films from citrus biowaste with intrinsic antimicrobial activity.
- Authors
Piacenza, Elena; Presentato, Alessandro; Alduina, Rosa; Scurria, Antonino; Pagliaro, Mario; Albanese, Lorenzo; Meneguzzo, Francesco; Ciriminna, Rosaria; Chillura Martino, Delia F.
- Abstract
Pectin recovered via hydrodynamic cavitation (IntegroPectin) from lemon and grapefruit agri-food waste intrinsically containing antimicrobial bioactive substances (flavonoids, phenolic acids, terpenes, and terpenoids) was used to generate innovative and eco-compatible films that efficiently inhibit the growth of Gram-negative pathogens. Extensive characterization of films confirmed the presence of these substances, which differently interact with the polysaccharide polymer (pectin), plasticizer (glycerol), surfactant (Tween 60), and cross-linker (Ca2+), conferring to these films a unique structure. Besides, IntegroPectin-based films constitute versatile systems for the sustained, controlled, and slow-release (up to 72 h) of bioactive substances in an aqueous environment. This feature is crucial for the good in vitro antimicrobial activity exerted by IntegroPectin films against three Gram-negative bacteria (two indicator pathogen strains Pseudomonas aeruginosa ATCC 10145, P. aeruginosa PAO1, and the clinical isolate Klebsiella pneumoniae) that are involved in the global emergence of the antimicrobial resistance.
- Subjects
PECTINS; ANTI-infective agents; CITRUS; GRAM-negative bacteria; KLEBSIELLA pneumoniae; PHENOLIC acids
- Publication
Cellulose, 2022, Vol 29, Issue 10, p5779
- ISSN
0969-0239
- Publication type
Article
- DOI
10.1007/s10570-022-04627-1