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- Title
Evaluation of a mobile phone-based, advanced symptom management system (ASyMS) in the management of chemotherapy-related toxicity.
- Authors
Kearney N; McCann L; Norrie J; Taylor L; Gray P; McGee-Lennon M; Sage M; Miller M; Maguire R; Kearney, N; McCann, L; Norrie, J; Taylor, L; Gray, P; McGee-Lennon, M; Sage, M; Miller, M; Maguire, R
- Abstract
<bold>Objectives: </bold>To evaluate the impact of a mobile phone-based, remote monitoring, advanced symptom management system (ASyMS) on the incidence, severity and distress of six chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand-foot syndrome and diarrhoea) in patients with lung, breast or colorectal cancer.<bold>Design: </bold>A two group (intervention and control) by five time points (baseline, pre-cycle 2, pre-cycle 3, pre-cycle 4 and pre-cycle 5) randomised controlled trial.<bold>Setting: </bold>Seven clinical sites in the UK; five specialist cancer centres and two local district hospitals.<bold>Participants: </bold>One hundred and twelve people with breast, lung or colorectal cancer receiving outpatient chemotherapy.<bold>Interventions: </bold>A mobile phone-based, remote monitoring, advanced symptom management system (ASyMS).<bold>Main Outcome Measures: </bold>Chemotherapy-related morbidity of six common chemotherapy-related symptoms (nausea, vomiting, fatigue, mucositis, hand-foot syndrome and diarrhoea).<bold>Results: </bold>There were significantly higher reports of fatigue in the control group compared to the intervention group (odds ratio = 2.29, 95%CI = 1.04 to 5.05, P = 0.040) and reports of hand-foot syndrome were on average lower in the control group (odds ratio control/intervention = 0.39, 95%CI = 0.17 to 0.92, P = 0.031).<bold>Conclusion: </bold>The study demonstrates that ASyMS can support the management of symptoms in patients with lung, breast and colorectal cancer receiving chemotherapy.
- Publication
Supportive Care in Cancer, 2009, Vol 17, Issue 4, p437
- ISSN
0941-4355
- Publication type
journal article
- DOI
10.1007/s00520-008-0515-0