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- Title
Predicting mortality in burn patients with bacteraemia.
- Authors
Ceniceros, Alexandra; Pértega, Sonia; Galeiras, Rita; Mourelo, Mónica; López, Eugenia; Broullón, Javier; Sousa, Dolores; Freire, David
- Abstract
Objective: To determine factors associated with mortality in burn patients with bacteraemia. Background: Previous studies have shown the negative impact of bacteraemia on the prognosis of burn patients, but only a few of these have analysed variables intervening in the clinical progress of these patients. Methods: A retrospective study of adult burn patients ( n = 73) with bacteraemia (103 episodes) in a Burns Unit during the 2000-2013 period. The study collected demographic variables, and comorbidity, injury-related and clinical data related to bacteraemia. Variables related to hospital mortality were analysed using a multiple logistic regression model. Results: The cumulative incidence of bacteraemia was 4.4 episodes/100 patients. The mean age was 53.3 ± 19.2 years (65.8 % male). The median total body surface area (TBSA) was 35 %, while 50.7 % of the population had inhalation syndrome. The mean SOFA score at the onset of bacteraemia was 2.7 ± 3.8. The most common pathogen was Pseudomonas aeruginosa (17.5 %). The mortality rate was 24.7 %. The variables that were significantly associated with mortality were age (OR = 1.13), TBSA (OR = 1.05), SOFA score at the onset of bacteraemia (OR = 1.53) and recurrent bacteraemia (OR = 41.6). Conclusion: In addition to conventional risk factors, recurrence and organ dysfunction at the onset of bacteraemia are also associated with mortality, while the pathogen involved is not a prognostic factor.
- Subjects
AGE distribution; BACTEREMIA; MULTIPLE organ failure; PSEUDOMONAS; COMORBIDITY; DISEASE relapse; BURN patients; MULTIPLE regression analysis; PREDICTIVE tests; DISEASE incidence; RETROSPECTIVE studies; DATA analysis software; SMOKE inhalation injuries; DESCRIPTIVE statistics; ODDS ratio; PROGNOSIS
- Publication
Infection, 2016, Vol 44, Issue 2, p215
- ISSN
0300-8126
- Publication type
Article
- DOI
10.1007/s15010-015-0847-x