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- Title
Long-term treatment of invasive sinus, tracheobroncheal, pulmonary and intracerebral aspergillosis in acute lymphoblastic leukaemia.
- Authors
Björkholm, M.; Kalin, M.; Grane, P.; Celsing, F.
- Abstract
A 59-year-old male with acute lymphoblastic leukemia developed sinus, tracheobroncheal, pulmonary, and intracerebral aspergillosis. All lesions except the intracerebral aspergillosis healed after combination antifungal treatment. Long-term voriconazole-but not posaconazole-therapy induced partial regression of the cerebral manifestations. At the time of writing, 3.5 years after the initial diagnosis, the patient is working half-time and suffers from a possible voriconazole-induced polyneuropathy.
- Subjects
LUNG microbiology; ANTIFUNGAL agents; ASPERGILLOSIS; BRAIN; LARYNX; LUNGS; LYMPHOBLASTIC leukemia; MAGNETIC resonance imaging; PARANASAL sinuses; PULMONARY aspergillosis; TOMOGRAPHY; DISEASE complications
- Publication
Infection, 2012, Vol 40, Issue 1, p81
- ISSN
0300-8126
- Publication type
Report
- DOI
10.1007/s15010-011-0158-9