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- Title
Elastography ultrasound for breast lesions: fat-to-lesion strain ratio vs gland-to-lesion strain ratio.
- Authors
Zhou, JianQiao; Zhou, Chun; Zhan, WeiWei; Jia, XiaoHong; Dong, YiJie; Yang, ZhiFang
- Abstract
Objective: To compare the diagnostic performance of the fat-to-lesion strain ratio (FLR) and gland-to-lesion strain ratio (GLR) in the diagnosis of breast lesions. Methods: This was an institutional ethics committee approved prospective study. One hundred and ninety-three breast lesions in 193 women (mean age, 46.03 ± 13.60 years, range 18-82 years) were examined with conventional and elastographic US. Both the FLR and GLR of the lesions were calculated. The elasticity scores of the lesions were also evaluated using the five-point elasticity scoring system. For diagnostic performance, the sensitivity, specificity and receiver operating characteristic (ROC) analysis were obtained. Results: Seventy lesions were malignant and 123 were benign. Both the FLR and GLR of the lesions were significantly higher in malignant cases than in benign ones ( P < 0.001 for both). The Az values for the FLR (0.847) and the elasticity score (0.829) were significantly higher than that for the GLR (0.752) ( P = 0.009, P = 0.029, respectively). However, there was no significant difference in the Az value between the FLR and the elasticity score ( P = 0.443). Conclusion: The FLR yielded better diagnostic performance than GLR in breast lesions; the fatty tissue was better than glandular tissue as the reference normal tissue for calculating strain ratio in breast elastography. Key Points: • FLR was higher than GLR in both malignant and benign breast lesions. • Both FLR and GLR were higher in malignant than in benign breast lesions. • FLR yielded better diagnostic performance than GLR in breast lesions.
- Subjects
BREAST imaging; ULTRASONIC imaging; TISSUE wounds; ADIPOSE tissues; MEDICAL radiology
- Publication
European Radiology, 2014, Vol 24, Issue 12, p3171
- ISSN
0938-7994
- Publication type
Article
- DOI
10.1007/s00330-014-3366-8