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- Title
Hep573 Study: A randomised, double-blind, placebo-controlled trial of silymarin alone and combined with antioxidants to improve liver function and quality of life in people with chronic hepatitis C.
- Authors
Salmond, S. J.; George, J.; Strasser, S. I.; Byth, K.; Rawlinson, B.; Mori, T. A.; Croft, K. D.; Adams, L. A.; Batey, R. G.
- Abstract
The article reports on a study that examined the impacts of two naturopathic treatments with antioxidant nutrients and herbal medicines against placebo on liver function and quality of life in chronic hepatitis C patients. It was done in three teaching hospitals in New South Wales, Australia. Study duration was 24 weeks on active treatment or placebo and 24 weeks follow-up post-treatment. Silymarin use with antioxidants had a higher rate of alanine aminotransferase than placebo or silymarin.
- Subjects
NEW South Wales; THERAPEUTIC use of antioxidants; LIVER physiology; ANALYSIS of variance; COMBINATION drug therapy; CHI-squared test; CONFIDENCE intervals; FLAVONOIDS; GAS chromatography; MASS spectrometry; PLACEBOS; QUALITY of life; QUESTIONNAIRES; RESEARCH funding; RNA; STATISTICAL sampling; MATHEMATICAL variables; PLANT extracts; OXIDATIVE stress; ALANINE aminotransferase; RANDOMIZED controlled trials; TREATMENT effectiveness; BLIND experiment; DESCRIPTIVE statistics; CHRONIC hepatitis C; GENOTYPES; KRUSKAL-Wallis Test; THERAPEUTICS
- Publication
Australian Journal of Herbal & Naturopathic Medicine, 2018, Vol 30, Issue 1, p12
- ISSN
2209-119X
- Publication type
Article