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- Title
Assignment of the phosphoinositide-3-kinase, class 3 (PIK3C3) gene to porcine chromosome 6q22→q23 by somatic cell and radiation hybrid panel mapping.
- Authors
Kim, J. H.; Lee, Y. S.; Park, E. W.; Seo, B. Y.; Cho, I. C.; Lee, J. G.; Oh, S. J.; Lee, J. H.; Jeon, J. T.
- Abstract
The article reports that phosphatidylinositide 3-kinases (PI3-kinases) constitute a lipid kinase family characterized by their ability to phosphorylate the inositol ring 3'-OH group in inositol phospholipids to generate the second messenger phosphatidylinositol-3,4,5-trisphosphate. These kinases participate in mitogenesis, glucose transport, regulation of hepatic glucose output, glycogen synthesis, and antilipolysis in typical insulin target cells such as liver, muscle, and fat.
- Subjects
PHOSPHOINOSITIDES; LIPIDS; INOSITOL; GLUCOSE; GLYCOGEN synthesis; LIPOLYSIS
- Publication
Cytogenetic & Genome Research, 2005, Vol 108, Issue 4, p362A
- ISSN
1424-8581
- Publication type
Article
- DOI
10.1159/000081533