We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
In-hospital outcomes for solid organ transplants according to type 2 diabetes status: An observational, 15-year study in Spain.
- Authors
de Miguel‐Yanes, José M.; Jiménez‐García, Rodrigo; de Miguel‐Díez, Javier; Hernández‐Barrera, Valentín; Méndez‐Bailón, Manuel; Muñoz‐Rivas, Nuria; López‐de‐Andrés, Ana; de Miguel-Yanes, José M; Jiménez-García, Rodrigo; de Miguel-Díez, Javier; Hernández-Barrera, Valentín; Méndez-Bailón, Manuel; Muñoz-Rivas, Nuria; López-de-Andrés, Ana
- Abstract
<bold>Aims: </bold>To describe trends and outcomes during admission for solid organ transplant in people with or without type 2 diabetes in Spain, 2001-2015.<bold>Methods: </bold>We used national hospital discharge data to select all hospital admissions for kidney, lung, heart, and liver transplant. We estimated admission rates stratified by type 2 diabetes status. We built Poisson regression models to compare the adjusted time trends in admission rates. We tested in-hospital mortality (IHM) in logistic regression analyses.<bold>Results: </bold>We identified 50 964 transplants (16.7% in people with type 2 diabetes): kidney, 30 919; lung, 2810; heart, 3649; liver, 13 586. The overall adjusted incidence rate ratios (95% confidence intervals) of admission in people with type 2 diabetes vs no diabetes were 2.4 (2.32-2.48) for kidney, 1.51 (1.33-1.70) for lung, 2.87 (2.63-3.13) for heart, and 4.16 (3.99-4.33) for liver transplant. In the multivariate analysis, IHM decreased significantly over time for all types of transplant. Type 2 diabetes independently predicted lower IHM during admission only for heart (Odds ratio, OR [95% CI] = 0.62 [0.47-0.81]) and liver transplant (OR [95% CI] = 0.69 [0.58-0.82]).<bold>Conclusions: </bold>Admission rates for solid organ transplant were higher in people with type 2 diabetes than in people without diabetes. Type 2 diabetes was associated with lower in-hospital mortality during admission for heart and liver transplant.
- Publication
International Journal of Clinical Practice, 2019, Vol 73, Issue 3, pN.PAG
- ISSN
1368-5031
- Publication type
journal article
- DOI
10.1111/ijcp.13283