We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Phthalate exposure and childhood obesity.
- Authors
Shin Hye Kim; Mi Jung Park
- Abstract
Phthalates are commonly used as plasticizers and vehicles for cosmetic ingredients. Phthalate metabolites have documented biochemical activity including activating peroxisome proliferator-activated receptor and antiandrogenic effects, which may contribute to the development of obesity. In vitro and in vivo studies suggest that phthalates have significant effects on the development of obesity, especially after prenatal exposure at low doses. Although few studies have examined the effects of phthalate on obesity development in humans, some work has shown that phthalates affect humans and animals similarly. In this paper, we review the possible mechanisms of phthalate-induced obesity, and discuss evidence supporting the role of phthalates in the development of obesity in humans.
- Subjects
PHYSIOLOGICAL effects of phthalate esters; RISK of childhood obesity; PEROXISOMES; DIETHYLHEXYL phthalate; ENDOCRINE disruptors
- Publication
Annals of Pediatric Endocrinology & Metabolism, 2014, Vol 19, Issue 2, p69
- ISSN
2287-1012
- Publication type
Article
- DOI
10.6065/apem.2014.19.2.69