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- Title
Exploration of radiotherapy strategy for brain metastasis patients with driver gene positivity in lung cancer.
- Authors
Qian Bi; Xin Lian; Jing Shen; Fuquan Zhang; Tao Xu
- Abstract
This document provides a summary of a study comparing the efficacy of targeted therapy and radiotherapy in controlling brain metastases in patients with lung cancer. The study included 88 patients, all of whom received targeted therapy during their treatment. The results showed that there was no significant difference in intracranial progression-free survival (iPFS) or overall survival (OS) between the two treatment groups. However, the radiotherapy-first regimen was found to be more effective in local control of metastatic lesions. The study concludes that further research is needed to determine the optimal treatment sequence for lung cancer brain metastasis. The text also references two medical studies, one examining the efficacy of brain radiotherapy combined with EGFR-TKI treatment for patients with EGFR-mutated non-small cell lung cancer and the other investigating the effects of conformal radiotherapy on prostate cancer patients with a history of invasive urological procedures. These studies provide valuable insights into potential treatment options and their associated side effects for patients with these specific conditions.
- Subjects
LUNG cancer; BRAIN metastasis; RADIOTHERAPY; GENETIC mutation; PROGRESSION-free survival
- Publication
Journal of Cancer, 2024, Vol 15, Issue 7, p1994
- ISSN
1837-9664
- Publication type
Article
- DOI
10.7150/jca.91875