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Il-10 signaling reduces survival in mouse models of synucleinopathy.
Published in:
NPJ Parkinson's Disease, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41531-021-00169-8
By:
- Cockey, Samuel G.;
- McFarland, Karen N.;
- Koller, Emily J.;
- Brooks, Mieu M. T.;
- Gonzalez De La Cruz, Elsa;
- Cruz, Pedro E.;
- Ceballos-Diaz, Carolina;
- Rosario, Awilda M.;
- Levites, Yona R.;
- Borchelt, David R.;
- Golde, Todd E.;
- Giasson, Benoit I.;
- Chakrabarty, Paramita
Publication type:
Article
Parkinson's disease associated with pure ATXN10 repeat expansion.
Published in:
NPJ Parkinson's Disease, 2017, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41531-017-0029-x
By:
- Schüle, Birgitt;
- McFarland, Karen N.;
- Lee, Kelsey;
- Tsai, Yu-Chih;
- Nguyen, Khanh-Dung;
- Sun, Chao;
- Liu, Mei;
- Byrne, Christie;
- Gopi, Ramesh;
- Huang, Neng;
- Langston, J. William;
- Clark, Tyson;
- Gil, Francisco Javier Jiménez;
- Ashizawa, Tetsudo
Publication type:
Article
Diffusion MRI relates to plasma Aβ42/40 in PET negative participants without dementia.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 4, p. 2830, doi. 10.1002/alz.13693
By:
- DeSimone, Jesse C.;
- Wang, Wei‐en;
- Loewenstein, David A.;
- Duara, Ranjan;
- Smith, Glenn E.;
- McFarland, Karen N.;
- Armstrong, Melissa J.;
- Weber, Darren M.;
- Barker, Warren;
- Coombes, Stephen A.;
- Vaillancourt, David E.
Publication type:
Article
MhcII Regulates Transmission of α-Synuclein-Seeded Pathology in Mice.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8175, doi. 10.3390/ijms23158175
By:
- Gonzalez De La Cruz, Elsa;
- Vo, Quan;
- Moon, Katie;
- McFarland, Karen N.;
- Weinrich, Mary;
- Williams, Tristan;
- Giasson, Benoit I.;
- Chakrabarty, Paramita
Publication type:
Article
Founder Effects of Spinocerebellar Ataxias in the American Continents and the Caribbean.
Published in:
Cerebellum, 2020, v. 19, n. 3, p. 446, doi. 10.1007/s12311-020-01109-7
By:
- Rodríguez-Labrada, Roberto;
- Martins, Ana Carolina;
- Magaña, Jonathan J.;
- Vazquez-Mojena, Yaimeé;
- Medrano-Montero, Jacqueline;
- Fernandez-Ruíz, Juan;
- Cisneros, Bulmaro;
- Teive, Helio;
- McFarland, Karen N.;
- Saraiva-Pereira, Maria Luiza;
- Cerecedo-Zapata, César M.;
- Gomez, Christopher M.;
- Ashizawa, Tetsuo;
- Velázquez-Pérez, Luis;
- Jardim, Laura Bannach
Publication type:
Article
Clinical utility of plasma Aβ42/40 ratio by LC-MS/MS in Alzheimer's disease assessment.
Published in:
Frontiers in Neurology, 2024, p. 01, doi. 10.3389/fneur.2024.1364658
By:
- Weber, Darren M.;
- Taylor, Steven W.;
- Lagier, Robert J.;
- Kim, Jueun C.;
- Goldman, Scott M.;
- Clarke, Nigel J.;
- Vaillancourt, David E.;
- Duara, Ranjan;
- McFarland, Karen N.;
- Wei-en Wang;
- Golde, Todd E.;
- Racke, Michael K.
Publication type:
Article
SMRT Sequencing of Long Tandem Nucleotide Repeats in SCA10 Reveals Unique Insight of Repeat Expansion Structure.
Published in:
PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0135906
By:
- McFarland, Karen N.;
- Liu, Jilin;
- Landrian, Ivette;
- Godiska, Ronald;
- Shanker, Savita;
- Yu, Fahong;
- Farmerie, William G.;
- Ashizawa, Tetsuo
Publication type:
Article
Expansion of the Spinocerebellar Ataxia Type 10 (SCA10) Repeat in a Patient with Sioux Native American Ancestry.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081342
By:
- Bushara, Khalaf;
- Bower, Matthew;
- Liu, Jilin;
- McFarland, Karen N.;
- Landrian, Ivette;
- Hutter, Diane;
- Teive, Hélio A. G.;
- Rasmussen, Astrid;
- Mulligan, Connie J.;
- Ashizawa, Tetsuo
Publication type:
Article
Genome-Wide Histone Acetylation Is Altered in a Transgenic Mouse Model of Huntington's Disease.
Published in:
PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041423
By:
- McFarland, Karen N.;
- Das, Sudeshna;
- Sun, Ting Ting;
- Leyfer, Dmitri;
- Eva Xia;
- Sangrey, Gavin R.;
- Kuhn, Alexandre;
- Luthi-Carter, Ruth;
- Clark, Timothy W.;
- Sadri-Vakili, Ghazaleh;
- Cha, Jang-Ho J.
Publication type:
Article
A case report of SPG11 mutations in a Chinese ARHSP-TCC family.
Published in:
2016
By:
- Linwei Zhang;
- McFarland, Karen N.;
- Jinsong Jiao;
- Yujuan Jiao;
- Zhang, Linwei;
- Jiao, Jinsong;
- Jiao, Yujuan
Publication type:
journal article
Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier – phenotypic variability in autosomal dominant Alzheimer's disease.
Published in:
Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-0891-3
By:
- Lloyd, Grace M.;
- Trejo-Lopez, Jorge A.;
- Xia, Yuxing;
- McFarland, Karen N.;
- Lincoln, Sarah J.;
- Ertekin-Taner, Nilüfer;
- Giasson, Benoit I.;
- Yachnis, Anthony T.;
- Prokop, Stefan
Publication type:
Article
Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression.
Published in:
Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0787-2
By:
- Sorrentino, Zachary A.;
- Goodwin, Marshall S.;
- Riffe, Cara J.;
- Dhillon, Jess-Karan S.;
- Xia, Yuxing;
- Gorion, Kimberly-Marie;
- Vijayaraghavan, Niran;
- McFarland, Karen N.;
- Golbe, Lawrence I.;
- Yachnis, Anthony T.;
- Giasson, Benoit I.
Publication type:
Article
Paradoxical effects of repeat interruptions on spinocerebellar ataxia type 10 expansions and repeat instability.
Published in:
European Journal of Human Genetics, 2013, v. 21, n. 11, p. 1272, doi. 10.1038/ejhg.2013.32
By:
- McFarland, Karen N;
- Liu, Jilin;
- Landrian, Ivette;
- Gao, Rui;
- Sarkar, Partha S;
- Raskin, Salmo;
- Moscovich, Mariana;
- Gatto, Emilia M;
- Teive, Hélio A G;
- Ochoa, Adriana;
- Rasmussen, Astrid;
- Ashizawa, Tetsuo
Publication type:
Article
Huntingtin Modulates Transcription, Occupies Gene Promoters In Vivo, and Binds Directly to DNA in a Polyglutamine-Dependent Manner.
Published in:
Journal of Neuroscience, 2008, v. 28, n. 42, p. 10720, doi. 10.1523/JNEUROSCI.2126-08.2008
By:
- Benn, Caroline L.;
- Tingting Sun;
- Sadri-Vakili, Ghazaleh;
- McFarland, Karen N.;
- DiRocco, Derek P.;
- Yohrling, George J.;
- Clark, Timothy W.;
- Bouzou, Bérengère;
- Cha, Jang-Ho J.
Publication type:
Article
Neural-Specific Inactivation of ShcA Results in Increased Embryonic Neural Progenitor Apoptosis and Microencephaly.
Published in:
2006
By:
- McFarland, Karen N.;
- Wilkes, Steven R.;
- Koss, Sarah E.;
- Ravichandran, Kodi S.;
- Mandell, James W.
Publication type:
Abstract
Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo.
Published in:
Life Science Alliance, 2021, v. 4, n. 7, p. 1, doi. 10.26508/lsa.202101108
By:
- McFarland, Karen N.;
- Ceballos, Carolina;
- Rosario, Awilda;
- Ladd, Thomas;
- Moore, Brenda;
- Golde, Griffin;
- Xue Wang;
- Allen, Mariet;
- Ertekin-Taner, Nilüfer;
- Funk, Cory C.;
- Robinson, Max;
- Baloni, Priyanka;
- Rappaport, Noa;
- Chakrabarty, Paramita;
- Golde, Todd E.
Publication type:
Article
Parkinson Disease and Autoimmune Disorders--What Can We Learn From Genome-wide Pleiotropy?
Published in:
JAMA Neurology, 2017, v. 74, n. 7, p. 769, doi. 10.1001/jamaneurol.2017.0843
By:
- McFarland, Nikolaus R.;
- McFarland, Karen N.;
- Golde, Todd E.
Publication type:
Article
Combinatorial model of amyloid β and tau reveals synergy between amyloid deposits and tangle formation.
Published in:
Neuropathology & Applied Neurobiology, 2022, v. 48, n. 2, p. 1, doi. 10.1111/nan.12779
By:
- Koller, Emily J.;
- Ibanez, Kristen R.;
- Vo, Quan;
- McFarland, Karen N.;
- Gonzalez De La Cruz, Elsa;
- Zobel, Lillian;
- Williams, Tristan;
- Xu, Guilian;
- Ryu, Daniel;
- Patel, Preya;
- Giasson, Benoit I.;
- Prokop, Stefan;
- Chakrabarty, Paramita
Publication type:
Article
Extended haplotype with rs41524547-G defines the ancestral origin of SCA10.
Published in:
Human Molecular Genetics, 2024, v. 33, n. 18, p. 1567, doi. 10.1093/hmg/ddae092
By:
- McFarland, Karen N;
- Tiwari, Anjana;
- Hashem, Vera;
- Zhang, Linwei;
- Zeng, Desmond;
- Vincent, Justin;
- Arredondo, Maria J;
- Johnson, Kristy L;
- Gan, Shi Rui;
- Yabe, Ichiro;
- Skov, Laurits;
- Rasmussen, Astrid;
- Ashizawa, Tetsuo
Publication type:
Article
Semantic intrusion errors are associated with plasma Ptau-181 among persons with amnestic mild cognitive impairment who are amyloid positive.
Published in:
Frontiers in Neurology, 2023, v. 14, p. 1, doi. 10.3389/fneur.2023.1179205
By:
- Curiel Cid, Rosie E.;
- Ortega, Alexandra;
- Crocco, Elizabeth A.;
- Hincapie, Diana;
- McFarland, Karen N.;
- Duara, Ranjan;
- Vaillancourt, David;
- DeKosky, Steven T.;
- Smith, Glenn;
- Sfakianaki, Efrosyni;
- Rosselli, Monica;
- Barker, Warren W.;
- Adjouadi, Malek;
- Barreto, Yarlenis;
- Feito, Yuleidys;
- Loewenstein, David A.
Publication type:
Article
Characterization of harpy/Rca1/emi1 mutants: Patterning in the absence of cell division.
Published in:
Developmental Dynamics, 2010, v. 239, n. 3, p. 828, doi. 10.1002/dvdy.22227
By:
- Riley, Bruce B.;
- Sweet, Elly M.;
- Heck, Rebecca;
- Evans, Adrienne;
- McFarland, Karen N.;
- Warga, Rachel M.;
- Kane, Donald A.
Publication type:
Article
Genetic locus half baked is necessary for morphogenesis of the ectoderm.
Published in:
Developmental Dynamics, 2005, v. 233, n. 2, p. 390
By:
- Karen N. McFarland;
- Rachel M. Warga;
- Donald A. Kane
Publication type:
Article
MeCP2: a novel Huntingtin interactor.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 4, p. 1036, doi. 10.1093/hmg/ddt499
By:
- McFarland, Karen N.;
- Huizenga, Megan N.;
- Darnell, Shayna B.;
- Sangrey, Gavin R.;
- Berezovska, Oksana;
- Cha, Jang-Ho J.;
- Outeiro, Tiago F.;
- Sadri-Vakili, Ghazaleh
Publication type:
Article
Plasma p‐tau217 concordance with amyloid PET among ethnically diverse older adults.
Published in:
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2024, v. 16, n. 3, p. 1, doi. 10.1002/dad2.12617
By:
- Asken, Breton M.;
- DeSimone, Jesse C.;
- Wang, Wei‐En;
- McFarland, Karen N.;
- Arias, Franchesca;
- Levy, Shellie‐Anne;
- Fiala, Jacob;
- Velez‐Uribe, Idaly;
- Mayrand, Robin P.;
- Sawada, Luana Okino;
- Freytes, Christian;
- Adeyosoye, Michael;
- Barker, Warren W.;
- Crocco, Elizabeth A.;
- DeKosky, Steven T.;
- Adjouadi, Malek;
- Rosselli, Monica;
- Marsiske, Michael;
- Armstrong, Melissa J.;
- Smith, Glenn E.
Publication type:
Article
Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways.
Published in:
Alzheimer's Research & Therapy, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13195-022-01044-1
By:
- Ibanez, Kristen R.;
- McFarland, Karen N.;
- Phillips, Jennifer;
- Allen, Mariet;
- Lessard, Christian B.;
- Zobel, Lillian;
- De La Cruz, Elsa Gonzalez;
- Shah, Shivani;
- Vo, Quan;
- Wang, Xue;
- Quicksall, Zachary;
- Ryu, Daniel;
- Funk, Cory;
- Ertekin-Taner, Nilüfer;
- Prokop, Stefan;
- Golde, Todd E.;
- Chakrabarty, Paramita
Publication type:
Article
Transgenic Models of Spinocerebellar Ataxia Type 10: Modeling a Repeat Expansion Disorder.
Published in:
Genes, 2012, v. 3, n. 3, p. 481, doi. 10.3390/genes3030481
By:
- McFarland, Karen N.;
- Ashizawa, Tetsuo
Publication type:
Article
Inheritance patterns of ATCCT repeat interruptions in spinocerebellar ataxia type 10 (SCA10) expansions.
Published in:
PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0175958
By:
- Landrian, Ivette;
- McFarland, Karen N.;
- Liu, Jilin;
- Mulligan, Connie J.;
- Rasmussen, Astrid;
- Ashizawa, Tetsuo
Publication type:
Article
Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy.
Published in:
Molecular Neurodegeneration, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13024-021-00453-4
By:
- Levites, Yona;
- Funk, Cory;
- Wang, Xue;
- Chakrabarty, Paramita;
- McFarland, Karen N.;
- Bramblett, Baxter;
- O'Neal, Veronica;
- Liu, Xufei;
- Ladd, Thomas;
- Robinson, Max;
- Allen, Mariet;
- Carrasquillo, Minerva M.;
- Dickson, Dennis;
- Cruz, Pedro;
- Ryu, Danny;
- Li, Hong-Dong;
- Price, Nathan D.;
- Ertekin-Taner, NIlüfer;
- Golde, Todd E.
Publication type:
Article

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