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- Title
Malignant Myoepithelial Carcinoma Expleomorphic Adenoma of the Hard Palate: An Aggressive Tumor with Diagnostic Dilemma.
- Authors
Shenoy, Ashok M.; Halkud, Rajshekar; Shivappa, Akshay; Chavan, Purshottam; Sunil, K. C.; Sarvadyna, Jagdish; Samskruthi, M.; Siddappa, K. T.; Biswas, Siddharth; Naik, Sudhir M.
- Abstract
Background/Objectives: Myoepithelial carcinomas are uncommon neoplasms that account for about 10% of all myoepitheliomas. The invasiveness varies from a locally aggressive to highly metastatic tumor which may arise de novo or in a pleomorphic adenoma. Myoepitheliomas arise from myoepithelial cells lacking ductal differentiation which exhibit both epithelial and smooth muscle cell elements. Case report: we report a case of palatal swelling excised 4 years back, as pleomorphic adenoma, which later recurred as malignant myoepithelial carcinoma expleomorphic adenoma of the palate. CECT of the paranasal air sinuses did not show any bony invasion of the hard palate. So he was given radical radiotherapy with concurrent chemotherapy but after 3 years developed recurrence and metastasis to the skin and the lungs. The patient was referred to oral chemotherapy on a palliative basis. Conclusion: Malignant myoepithelial carcinoma expleomorphic adenoma of the hard palate is a highly aggressive rare tumor of the hard palate. Radical management with surgery and adjuvant chemoradiotherapy improves survival in these patients. Followup with metastatic workup should be accurate as the tumor is highly aggressive with poor prognosis.
- Subjects
ADENOMA; TUMORS; SMOOTH muscle; RADIOTHERAPY; FIBROADENOMAS
- Publication
International Journal of Head & Neck Surgery, 2014, Vol 5, Issue 2, p72
- ISSN
0975-7899
- Publication type
Article
- DOI
10.5005/jp-journals-10001-1185