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- Title
Is B-type natriuretic peptide clinically useful after pediatric heart transplantation?
- Authors
Das, Bibhuti B.
- Abstract
The evidence for BNP-guided management of pediatric heart transplant recipients is scarce. A search in PubMed with no date or language restriction resulted in 8 studies reporting relation between BNP and rejection, 2 studies on the time course of BNP levels after heart transplantation, one study each reporting relationship of BNP with cardiac allograft vasculopathy and post-transplant mortality. So far, the data available can only support BNP as an adjunctive marker, not a stand-alone test, in the screening of hemodynamically significant cardiac pathology in pediatric heart transplant recipients. A serial intraindividual measurements of BNP level rather than an absolute cut-off value, can be useful in combination with the patient's clinical condition to facilitate management of post-heart transplant care in children.
- Subjects
HEART transplantation; BRAIN natriuretic factor; HEART transplant recipients; ORGAN transplant waiting lists; ABSOLUTE value; CHILD care; PEDIATRIC pathology
- Publication
Trends in Transplantation, 2019, Vol 12, Issue 1, p1
- ISSN
1887-455X
- Publication type
Article
- DOI
10.15761/TiT.1000257