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- Title
Controllable Regioselective Construction of Both Functional α-Methylene-β- and -γ-amino Acid Derivatives Through an Organocatalyzed Tandem Allylic Alkylation and Amination.
- Authors
Pan, Feng; Chen, Jian-Ming; Qin, Tian-You; Zhang, Sean Xiao-An; Liao, Wei-Wei
- Abstract
A new controllable and regioselective allylic alkylation and amination reaction has been developed for the highly selective construction of compounds containing α-alkylidene-β-amino acid and α-methylene-γ-butyrolactam moieties. Furthermore, on the basis of this controllable strategy, multicomponent tandem reactions have also been accomplished. The subsequent transformations of the densely functionalized products have readily afforded a range of useful building blocks, which have potential utility in organic synthesis.
- Publication
European Journal of Organic Chemistry, 2012, Vol 2012, Issue 27, p5324
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.201200642