We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Acute effects of non-invasive ventilatory support on functional mitral regurgitation in patients with exacerbation of congestive heart failure.
- Authors
Bellone, Andrea; Barbieri, Andrea; Ricci, Caterina; Iori, Emilio; Donateo, Mario; Massobrio, Monica; Bendinelli, Stefano
- Abstract
Objective. The purpose of this study was to evaluate the acute effects of continuous positive airway pressure (CPAP) and bi-level airway pressure (BiPAP) on functional mitral regurgitation (MR) in patients with acute exacerbation of severe chronic congestive heart failure (CHF). Design. A cross-over study. Setting. A cardiopulmonary intensive care unit. Patients and interventions. Ten male patients affected by an acute exacerbation of congestive heart failure and hemodynamically significant MR were submitted to an echocardiograph color Doppler ultrasound evaluation during CPAP and BiPAP non-invasive ventilation. We analyzed left ventricle ejection fraction, area of MR and deceleration time (Dec-t). Outcome measures. The primary end point was to evaluate whether CPAP and BiPAP were effective in reducing functional MR. Results. After 30 min, the area of MR decreased from 10.0±2.7 to 8.0±2.9 cm2 with CPAP and from 9.9±2.6 to 8.6±2.6 cm2 with BiPAP (p<0.01); Dec-t increased from 120.9±12.7 to 136.0±8.7 ms after CPAP and from 120.5±11.4 to 134.2±13.6 ms after BiPAP (p<0.01). Conclusion. In patients with exacerbation of severe CHF and functional MR, both modalities of non-invasive ventilation (CPAP and BiPAP) significantly improved ejection fraction and were equally effective in reducing MR.
- Subjects
CONGESTIVE heart failure; HEART failure; MITRAL valve insufficiency; HEART diseases; CRITICAL care medicine; AIRWAY (Anatomy)
- Publication
Intensive Care Medicine, 2002, Vol 28, Issue 9, p1348
- ISSN
0342-4642
- Publication type
Article
- DOI
10.1007/s00134-002-1424-1