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- Title
Persistent Secondary Hyperparathyroidism and Vertebral Fractures in Kidney Transplantation: Role of Calcium-Sensing Receptor Polymorphisms and Vitamin D Deficiency.
- Authors
Giannini, Sandro; Sella, Stefania; Netto, Fatima Silva; Cattelan, Catia; Carbonare, Luca Dalle; Lazzarin, Roberta; Marchini, Francesco; Rigotti, Paolo; Marcocci, Claudio; Cetani, Filomena; Pardi, Elena; D'Angelo, Angela; Realdi, Giuseppe; Bonfante, Luciana
- Abstract
The article discusses the result of a study which investigated the role of vitamin D deficiency and calcium-sensing receptor polymorphisms in persistent vertebral fractures and secondary hyperparathyroidism (SHPT) in kidney transplantation. It was found that low 25-vitamin D is involved in the pathogenesis of SHPT and it is a common feature after kidney transplantation. The study also suggests that high parathyroid hormone level is associated with an increased risk for vertebral fractures.
- Subjects
HYPERPARATHYROIDISM; BONE fractures; KIDNEY transplantation; VITAMIN D deficiency; PARATHYROID hormone
- Publication
Journal of Bone & Mineral Research, 2010, Vol 25, Issue 4, p841
- ISSN
0884-0431
- Publication type
Article
- DOI
10.1359/jbmr.091025