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Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia.
Published in:
Cancer & Metabolism, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40170-023-00305-3
By:
- Rutten, Martijn G. S.;
- Lei, Yu;
- Hoogerland, Joanne H.;
- Bloks, Vincent W.;
- Yang, Hong;
- Bos, Trijnie;
- Krishnamurthy, Kishore A.;
- Bleeker, Aycha;
- Koster, Mirjam H.;
- Thomas, Rachel E.;
- Wolters, Justina C.;
- van den Bos, Hilda;
- Mithieux, Gilles;
- Rajas, Fabienne;
- Mardinoglu, Adil;
- Spierings, Diana C. J.;
- de Bruin, Alain;
- van de Sluis, Bart;
- Oosterveer, Maaike H.
Publication type:
Article
Alterations in Brain Cholesterol Metabolism in the APPSLxPS1mut mouse, a Model for Alzheimer's Disease.
Published in:
Journal of Alzheimer's Disease, 2010, v. 19, n. 1, p. 117, doi. 10.3233/JAD-2010-1209
By:
- Vanmierlo, Tim;
- Bloks, Vincent W.;
- Van Vark-van der Zee, Leonie C.;
- Rutten, Kris;
- Kerksiek, Anja;
- Friedrichs, Silvia;
- Sijbrands, Eric;
- Steinbusch, Harry W.;
- Kuipers, Folkert;
- Lütjohann, Dieter;
- Mulder, Monique
Publication type:
Article
Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-06479-y
By:
- Blankestijn, Maaike;
- Bloks, Vincent W.;
- Struik, Dicky;
- Huijkman, Nicolette;
- Kloosterhuis, Niels;
- Wolters, Justina C.;
- Wanders, Ronald J. A.;
- Vaz, Frédéric M.;
- Islinger, Markus;
- Kuipers, Folkert;
- van de Sluis, Bart;
- Groen, Albert K.;
- Verkade, Henkjan J.;
- Jonker, Johan W.
Publication type:
Article
Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 2, p. 1290, doi. 10.3390/ijms24021290
By:
- Zhan, Na;
- Wang, Boyang;
- Martens, Nikita;
- Liu, Yankai;
- Zhao, Shangge;
- Voortman, Gardi;
- van Rooij, Jeroen;
- Leijten, Frank;
- Vanmierlo, Tim;
- Kuipers, Folkert;
- Jonker, Johan W.;
- Bloks, Vincent W.;
- Lütjohann, Dieter;
- Palumbo, Marcella;
- Zimetti, Francesca;
- Adorni, Maria Pia;
- Liu, Hongbing;
- Mulder, Monique T.
Publication type:
Article
Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts.
Published in:
Diabetologia, 2022, v. 65, n. 5, p. 763, doi. 10.1007/s00125-022-05652-2
By:
- Fraszczyk, Eliza;
- Spijkerman, Annemieke M. W.;
- Zhang, Yan;
- Brandmaier, Stefan;
- Day, Felix R.;
- Zhou, Li;
- Wackers, Paul;
- Dollé, Martijn E. T.;
- Bloks, Vincent W.;
- Gào, Xīn;
- Gieger, Christian;
- Kooner, Jaspal;
- Kriebel, Jennifer;
- Picavet, H. Susan J.;
- Rathmann, Wolfgang;
- Schöttker, Ben;
- Loh, Marie;
- Verschuren, W. M. Monique;
- van Vliet-Ostaptchouk, Jana V.;
- Wareham, Nicholas J.
Publication type:
Article
Hepatic Farnesoid X-Receptor Isoforms α2 and α4 Differentially Modulate Bile Salt and Lipoprotein Metabolism in Mice.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0115028
By:
- Boesjes, Marije;
- Bloks, Vincent W.;
- Hageman, Jurre;
- Bos, Trijnie;
- van Dijk, Theo H.;
- Havinga, Rick;
- Wolters, Henk;
- Jonker, Johan W.;
- Kuipers, Folkert;
- Groen, Albert K.
Publication type:
Article
Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study.
Published in:
BMC Medicine, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12916-022-02688-4
By:
- Doestzada, Marwah;
- Zhernakova, Daria V.;
- C. L. van den Munckhof, Inge;
- Wang, Daoming;
- Kurilshikov, Alexander;
- Chen, Lianmin;
- Bloks, Vincent W.;
- van Faassen, Martijn;
- Rutten, Joost H. W.;
- Joosten, Leo A. B.;
- Netea, Mihai G.;
- Wijmenga, Cisca;
- Riksen, Niels P.;
- Zhernakova, Alexandra;
- Kuipers, Folkert;
- Fu, Jingyuan
Publication type:
Article
Short‐term protein restriction at advanced age stimulates FGF21 signalling, energy expenditure and browning of white adipose tissue.
Published in:
FEBS Journal, 2021, v. 288, n. 7, p. 2257, doi. 10.1111/febs.15604
By:
- Dommerholt, Marleen B.;
- Blankestijn, Maaike;
- Vieira‐Lara, Marcel A.;
- van Dijk, Theo H.;
- Wolters, Henk;
- Koster, Mirjam H.;
- Gerding, Albert;
- van Os, Ronald P.;
- Bloks, Vincent W.;
- Bakker, Barbara M.;
- Kruit, Janine K.;
- Jonker, Johan W.
Publication type:
Article
DNA methylation trajectories and accelerated epigenetic aging in incident type 2 diabetes.
Published in:
GeroScience, 2022, v. 44, n. 6, p. 2671, doi. 10.1007/s11357-022-00626-z
By:
- Fraszczyk, Eliza;
- Thio, Chris H. L.;
- Wackers, Paul;
- Dollé, Martijn E. T.;
- Bloks, Vincent W.;
- Hodemaekers, Hennie;
- Picavet, H. Susan;
- Stynenbosch, Marjolein;
- Verschuren, W. M. Monique;
- Snieder, Harold;
- Spijkerman, Annemieke M. W.;
- Luijten, Mirjam
Publication type:
Article
Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD<sup>+</sup> in medium-chain acyl-CoA dehydrogenase knockout mice.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-50758-0
By:
- Martines, Anne-Claire M. F.;
- Gerding, Albert;
- Stolle, Sarah;
- Vieira-Lara, Marcel A.;
- Wolters, Justina C.;
- Jurdzinski, Angelika;
- Bongiovanni, Laura;
- de Bruin, Alain;
- van der Vlies, Pieter;
- van der Vries, Gerben;
- Bloks, Vincent W.;
- Derks, Terry G. J.;
- Reijngoud, Dirk-Jan;
- Bakker, Barbara M.
Publication type:
Article
Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet.
Published in:
PLoS ONE, 2020, v. 15, n. 9, p. 1, doi. 10.1371/journal.pone.0232069
By:
- Ronda, Onne A. H. O.;
- van de Heijning, Bert J. M.;
- de Bruin, Alain;
- Thomas, Rachel E.;
- Martini, Ingrid;
- Koehorst, Martijn;
- Gerding, Albert;
- Koster, Mirjam H.;
- Bloks, Vincent W.;
- Jurdzinski, Angelika;
- Mulder, Niels L.;
- Havinga, Rick;
- van der Beek, Eline M.;
- Reijngoud, Dirk-Jan;
- Kuipers, Folkert;
- Verkade, Henkjan J.
Publication type:
Article
Epigenetic programming at the Mogat1 locus may link neonatal overnutrition with long-term hepatic steatosis and insulin resistance.
Published in:
FASEB Journal, 2018, v. 32, n. 11, p. 6025, doi. 10.1096/fj.201700717RR
By:
- Ramon-Krauel, Marta;
- Pentinat, Thais;
- Bloks, Vincent W.;
- Cebrià, Judith;
- Ribo, Silvia;
- Pérez-Wienese, Ricky;
- Vilà, Maria;
- Palacios-Marin, Ivonne;
- Fernández-Pérez, Antonio;
- Vallejo, Mario;
- Téllez, Noèlia;
- Rodríguez, Miguel Àngel;
- Yanes, Oscar;
- Lerin, Carles;
- Díaz, Rubén;
- Plosch, Torsten;
- Tietge, Uwe J. F.;
- Jimenez-Chillaron, Josep C.
Publication type:
Article
Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice.
Published in:
2011
By:
- Vanmierlo T;
- Rutten K;
- van Vark-van der Zee LC;
- Friedrichs S;
- Bloks VW;
- Blokland A;
- Ramaekers FC;
- Sijbrands E;
- Steinbusch H;
- Prickaerts J;
- Kuipers F;
- Lütjohann D;
- Mulder M;
- Vanmierlo, Tim;
- Rutten, Kris;
- van Vark-van der Zee, Leonie C;
- Friedrichs, Silvia;
- Bloks, Vincent W;
- Blokland, Arjan;
- Ramaekers, Frans C
Publication type:
journal article
Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90687-5
By:
- van der Schoor, Lori W. E.;
- Verkade, Henkjan J.;
- Bertolini, Anna;
- de Wit, Sanne;
- Mennillo, Elvira;
- Rettenmeier, Eva;
- Weber, André A.;
- Havinga, Rick;
- Valášková, Petra;
- Jašprová, Jana;
- Struik, Dicky;
- Bloks, Vincent W.;
- Chen, Shujuan;
- Schreuder, Andrea B.;
- Vítek, Libor;
- Tukey, Robert H.;
- Jonker, Johan W.
Publication type:
Article
The effects of bariatric surgery on clinical profile, DNA methylation, and ageing in severely obese patients.
Published in:
Clinical Epigenetics, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13148-019-0790-2
By:
- Fraszczyk, Eliza;
- Luijten, Mirjam;
- Spijkerman, Annemieke M. W.;
- Snieder, Harold;
- Wackers, Paul F. K.;
- Bloks, Vincent W.;
- Nicoletti, Carolina F.;
- Nonino, Carla B.;
- Crujeiras, Ana B.;
- Buurman, Wim A.;
- Greve, Jan Willem;
- Rensen, Sander S.;
- Wolffenbuttel, Bruce H. R.;
- van Vliet-Ostaptchouk, Jana V.
Publication type:
Article
Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70 −/− Mice with a Human-like Bile Acid Composition.
Published in:
Biomedicines, 2023, v. 11, n. 9, p. 2495, doi. 10.3390/biomedicines11092495
By:
- Palmiotti, Anna;
- de Vries, Hilde D.;
- Hovingh, Milaine V.;
- Koehorst, Martijn;
- Mulder, Niels L.;
- Verkade, Esther;
- Veentjer, Melany K.;
- van Dijk, Theo H.;
- Bloks, Vincent W.;
- Havinga, Rick;
- Verkade, Henkjan J.;
- de Boer, Jan Freark;
- Kuipers, Folkert
Publication type:
Article
Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition.
Published in:
Clinical Science, 2023, v. 137, n. 21, p. 1637, doi. 10.1042/CS20230812
By:
- Verkade, Esther;
- Wenqiang Shen;
- Hovingh, Milaine V.;
- Mulder, Niels L.;
- de Bruyn, Krisztina;
- Koehorst, Martijn;
- de Vries, Hilde D.;
- Bloks, Vincent W.;
- Kuipers, Folkert;
- Freark de Boer, Jan
Publication type:
Article

Found: 17