We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Understanding the Signaling Pathways Related to the Mechanism and Treatment of Diabetic Peripheral Neuropathy.
- Authors
Tang, He-yong; Jiang, Ai-juan; Ma, Jun-long; Wang, Fan-jing; Shen, Guo-ming
- Abstract
Worldwide, the most prevalent metabolic disorder is diabetes mellitus (DM), an important condition that has been widely studied. Diabetic peripheral neuropathy (DPN), a complication that can occur with DM, is associated with pain and can result in foot ulcers and even amputation. DPN treatments are limited and mainly focus on pain management. There is a clear need to develop treatments for DPN at all stages. To make this progress, it is necessary to understand the molecular signaling pathways related to DPN. For this review, we aimed to concentrate on the main signaling cascades that contribute to DPN. In addition, we provide information with regard to treatments that are being explored.
- Subjects
DIABETIC neuropathies; PERIPHERAL neuropathy; METABOLIC disorders; FOOT ulcers; PAIN management; DIABETES; THERAPEUTICS
- Publication
Endocrinology, 2019, Vol 160, Issue 9, p2119
- ISSN
0013-7227
- Publication type
Article
- DOI
10.1210/en.2019-00311