We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A meta-analysis of Shenqi Fuzheng combined with radiation in the treatment of nonsmall cell lung cancer.
- Authors
Huijuan Jiang; Hongzhi Zhang; Xigang Hu; Jing Ma
- Abstract
Objective: The objective of this study is to evaluate the efficacy and toxicity reduction of Shenqi Fuzheng injection in the treatment of nonsmall cell lung cancer (NSCLC). Materials and Methods: Through searching the PubMed, WANFANG and CNKI, we recruited clinical trials related to Shenqi Fuzheng combined with radiation in the treatment of NSCLC. We extracted the treatment effective data and radiation related toxicities data. The clinical efficacy and radiation toxicity was pooled by meta-analysis. The statistical heterogeneity was evaluated by I2 tests. Results: By searching the related databases, we finally included 7 studies in this meta-analysis. The pooled results indicated that Shenqi Fuzheng injection can improve the clinical efficacy (relative risk [RR] =1.27, 95% confidence interval [CI]: 1.13-1.43), and decrease the radiation pneumonia (RR = 0.41, 95% CI: 0.26-0.46), radiation esophagitis (RR = 0.46, 95% CI: 0.37-0.59) and bone marrow suppression (RR = 0.44, 95% CI: 0.36-0.53). Conclusion: Shenqi Fuzheng injection can improve the clinical efficacy and decrease the radiation toxicities in the NSCLC patients treated with radiation.
- Subjects
NON-small-cell lung carcinoma; META-analysis; PNEUMONIA; CLINICAL trials; PNEUMONIA treatment; RADIOTHERAPY; PATIENTS
- Publication
Journal of Cancer Research & Therapeutics, 2015, Vol 11, pC101
- ISSN
0973-1482
- Publication type
Article
- DOI
10.4103/0973-1482.163855