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- Title
Anatomic Repair of Congenitally Corrected Transposition: Reappraisal of Eligibility Criteria.
- Authors
Weixler, Viktoria H. M.; Kramer, Peter; Murin, Peter; Romanchenko, Olga; Cho, Mi-Young; Ovroutski, Stanislav; Hübler, Michael; Berger, Felix; Photiadis, Joachim
- Abstract
Several criteria to identify suitable candidates for anatomic repair in congenitally corrected transposition (cc-TGA) have been proposed. The purpose of this study was to critically re-evaluate adequacy of these recommendations in our patient cohort. All cc-TGA patients undergoing anatomic repair between 2010 and 2019 were reviewed. Evaluated eligibility criteria for repair included age ≤ 15 years, LV mass index ≥ 45–50 g/m2, LV mass/volume ratio > 0.9–1.5 and systolic LV to right ventricle pressure ratio > 70–90% among others. Repair failure was defined as postoperative early mortality or LV dysfunction requiring mechanical circulatory support. Twenty-five patients were included (median [interquartile range] age at surgery 1.8 years [0.7;6.6]; median postoperative follow-up 3.2 years [0.7;6.3]). Median preoperative LV ejection fraction was 60% [56;64], indexed LV mass 48.5 g/m2 [43.7;58.1] and LV mass/volume ratio 1.5 [1.1;1.6], respectively. A total of 12 patients (48%) did not meet at least one of the previously recommended criteria, however, all but two patients (92%) experienced favorable early outcome. Of 7 patients (28%) with indexed LV mass < 45 g/m2, 6 were successfully operated. There were two early repair failures (8%) with LV dysfunction: one patient died and one required mechanical circulatory support but recovered well. Surgery was performed successfully in patients with LV mass and volume Z-scores as low as − 2 and − 2.5, respectively. Anatomic correction for cc-TGA can be performed with excellent early outcome and is feasible even in patients with LV mass below previously recommended cut-offs. The use of LV mass and volume Z-scores might help to refine eligibility criteria.
- Subjects
ARTIFICIAL blood circulation; LEFT ventricular dysfunction; HEART assist devices
- Publication
Pediatric Cardiology, 2022, Vol 43, Issue 6, p1214
- ISSN
0172-0643
- Publication type
Article
- DOI
10.1007/s00246-022-02841-z