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- Title
State-of-the-art gene-based therapies: the road ahead.
- Authors
Kay, Mark A.
- Abstract
Improvements in the gene transfer vectors used in therapeutic trials have led to substantial clinical successes in patients with serious genetic conditions, such as immunodeficiency syndromes, blindness and some cancer types. Several barriers need to be overcome before this type of therapy becomes a widely accepted treatment for a broad group of medical diseases. However, recent progress in the field is finally realizing some of the promises made more than 20 years ago, providing optimism for additional successes in the near future.
- Subjects
GENETIC transformation; IMMUNOLOGICAL deficiency syndrome treatment; BLINDNESS; GENE therapy; CANCER patients
- Publication
Nature Reviews Genetics, 2011, Vol 12, Issue 5, p316
- ISSN
1471-0056
- Publication type
Article
- DOI
10.1038/nrg2971