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- Title
Editorial: Immune tolerance and human malaria.
- Authors
Dobbs, Katherine Rose; Jagannathan, Prasanna; Dechavanne, Celia
- Abstract
This article, titled "Editorial: Immune tolerance and human malaria," explores the relationship between immune tolerance and malaria. The authors discuss how exposure to malaria parasites can affect susceptibility to malaria and other pathogens. They also examine the mechanisms underlying immune tolerance to blood-stage infection and the role of immunoregulatory cells in limiting immunopathology. The article highlights the potential impact of malaria-induced immune tolerance on vaccine efficacy and suggests strategies to overcome immune tolerance to improve vaccine effectiveness. The authors present several studies that investigate the modulation of immune responses during malaria infection and its implications for host protection and vaccine development.
- Subjects
ADENOSINES; IMMUNOLOGICAL tolerance; MALARIA; MONONUCLEAR leukocytes
- Publication
Frontiers in Immunology, 2024, p1
- ISSN
1664-3224
- Publication type
Article
- DOI
10.3389/fimmu.2024.1450480