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- Title
Isolation, tissue expression, and chromosomal assignment of a novel human gene which encodes a protein with RING finger motif.
- Authors
Seki, Naohiko; Hattori, Atsushi; Sugano, Sumio; Suzuki, Yutaka; Nakagawara, Akira; Ohhira, M.; Muramatsu, Masa-aki; Hori, Tada-aki; Saito, T.
- Abstract
Abstract We identified a novel gene encoding a RING finger (C3HC4-type zinc finger) protein from a human neuroblastoma full-length enriched cDNA library. This cDNA clone consists of 1919 nucleotides with an open reading frame of a 485-amino acid protein. From reverse transcription (RT)-polymerase chain reaction (PCR) analysis, the messenger RNA was ubiquitously expressed in various human adult tissues. The chromosomal location of the gene was determined on the chromosome 6p21.3 region by PCR-based analyses with both a human/rodent monochromosomal hybrid cell panel and a radiation hybrid mapping panel.
- Subjects
GENES; PROTEINS; NEUROBLASTOMA; AMINO acids; POLYMERASE chain reaction
- Publication
Journal of Human Genetics, 1998, Vol 43, Issue 4, p272
- ISSN
1434-5161
- Publication type
Article
- DOI
10.1007/s100380050088