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Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition.
Published in:
Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.854031
By:
- Blume, Tanja;
- Deussing, Maximilian;
- Biechele, Gloria;
- Peters, Finn;
- Zott, Benedikt;
- Schmidt, Claudio;
- Franzmeier, Nicolai;
- Wind, Karin;
- Eckenweber, Florian;
- Sacher, Christian;
- Shi, Yuan;
- Ochs, Katharina;
- Kleinberger, Gernot;
- Xiang, Xianyuan;
- Focke, Carola;
- Lindner, Simon;
- Gildehaus, Franz-Josef;
- Beyer, Leonie;
- von Ungern-Sternberg, Barbara;
- Bartenstein, Peter
Publication type:
Article
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
Published in:
EMBO Molecular Medicine, 2020, v. 12, n. 4, p. 1, doi. 10.15252/emmm.201911227
By:
- Schlepckow, Kai;
- Monroe, Kathryn M;
- Kleinberger, Gernot;
- Cantuti‐Castelvetri, Ludovico;
- Parhizkar, Samira;
- Xia, Dan;
- Willem, Michael;
- Werner, Georg;
- Pettkus, Nadine;
- Brunner, Bettina;
- Sülzen, Alice;
- Nuscher, Brigitte;
- Hampel, Heike;
- Xiang, Xianyuan;
- Feederle, Regina;
- Tahirovic, Sabina;
- Park, Joshua I;
- Prorok, Rachel;
- Mahon, Cathal;
- Liang, Chun‐Chi
Publication type:
Article
TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
Published in:
EMBO Molecular Medicine, 2016, v. 8, n. 9, p. 992, doi. 10.15252/emmm.201606370
By:
- Xiang, Xianyuan;
- Werner, Georg;
- Bohrmann, Bernd;
- Liesz, Arthur;
- Mazaheri, Fargol;
- Capell, Anja;
- Feederle, Regina;
- Knuesel, Irene;
- Kleinberger, Gernot;
- Haass, Christian
Publication type:
Article
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
Published in:
EMBO Journal, 2017, v. 36, n. 13, p. 1837, doi. 10.15252/embj.201796516
By:
- Kleinberger, Gernot;
- Brendel, Matthias;
- Mracsko, Eva;
- Wefers, Benedikt;
- Groeneweg, Linda;
- Xiang, Xianyuan;
- Focke, Carola;
- Deußing, Maximilian;
- Suárez‐Calvet, Marc;
- Mazaheri, Fargol;
- Parhizkar, Samira;
- Pettkus, Nadine;
- Wurst, Wolfgang;
- Feederle, Regina;
- Bartenstein, Peter;
- Mueggler, Thomas;
- Arzberger, Thomas;
- Knuesel, Irene;
- Rominger, Axel;
- Haass, Christian
Publication type:
Article
Depletion and activation of microglia impact metabolic connectivity of the mouse brain.
Published in:
Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02735-8
By:
- Gnörich, Johannes;
- Reifschneider, Anika;
- Wind, Karin;
- Zatcepin, Artem;
- Kunte, Sebastian T.;
- Beumers, Philipp;
- Bartos, Laura M.;
- Wiedemann, Thomas;
- Grosch, Maximilian;
- Xiang, Xianyuan;
- Fard, Maryam K.;
- Ruch, Francois;
- Werner, Georg;
- Koehler, Mara;
- Slemann, Luna;
- Hummel, Selina;
- Briel, Nils;
- Blume, Tanja;
- Shi, Yuan;
- Biechele, Gloria
Publication type:
Article
Single cell radiotracer allocation via immunomagentic sorting (scRadiotracing) to disentangle PET signals at cellular resolution.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 10, p. 1, doi. 10.2967/jnumed.122.264171
By:
- Bartos, Laura M.;
- Kunte, Sebastian T.;
- Beumers, Philipp;
- Xiang, Xianyuan;
- Wind, Karin;
- Ziegler, Sibylle;
- Bartenstein, Peter;
- Choi, Hongyoon;
- Lee, Dong Soo;
- Haass, Christian;
- Baumgarten, Louisa von;
- Tahirovic, Sabina;
- Albert, Nathalie L.;
- Lindner, Simon;
- Brendel, Matthias
Publication type:
Article
Single cell radiotracer allocation via immunomagentic sorting (scRadiotracing) to disentangle PET signals at cellular resolution.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 9, p. 1, doi. 10.2967/jnumed.122.264171
By:
- Bartos, Laura M.;
- Kunte, Sebastian T.;
- Beumers, Philipp;
- Xianyuan Xiang;
- Wind, Karin;
- Ziegler, Sibylle;
- Bartenstein, Peter;
- Hongyoon Choi;
- Dong Soo Lee;
- Haass, Christian;
- von Baumgarten, Louisa;
- Tahirovic, Sabina;
- Albert, Nathalie L.;
- Lindner, Simon;
- Brendel, Matthias
Publication type:
Article
Single cell radiotracer allocation via immunomagentic sorting (scRadiotracing) to disentangle PET signals at cellular resolution.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 7, p. 1, doi. 10.2967/jnumed.122.264171
By:
- Bartos, Laura M.;
- Kunte, Sebastian T.;
- Beumers, Philipp;
- Xianyuan Xiang;
- Wind, Karin;
- Ziegler, Sibylle;
- Bartenstein, Peter;
- Hongyoon Choi;
- Dong Soo Lee;
- Haass, Christian;
- von Baumgarten, Louisa;
- Tahirovic, Sabina;
- Albert, Nathalie L.;
- Lindner, Simon;
- Brendel, Matthias
Publication type:
Article
Single cell radiotracer allocation via immunomagentic sorting (scRadiotracing) to disentangle PET signals at cellular resolution.
Published in:
Journal of Nuclear Medicine, 2022, v. 63, n. 6, p. 1, doi. 10.2967/jnumed.122.264171
By:
- Bartos, Laura M.;
- Kunte, Sebastian T.;
- Beumers, Philipp;
- Xianyuan Xiang;
- Wind, Karin;
- Ziegler, Sibylle;
- Bartenstein, Peter;
- Hongyoon Choi;
- Dong Soo Lee;
- Haass, Christian;
- von Baumgarten, Louisa;
- Tahirovic, Sabina;
- Albert, Nathalie L.;
- Lindner, Simon;
- Brendel, Matthias
Publication type:
Article
TREM2 promotes glioma progression and angiogenesis mediated by microglia/brain macrophages.
Published in:
Glia, 2023, v. 71, n. 11, p. 2679, doi. 10.1002/glia.24456
By:
- Chen, Xuezhen;
- Zhao, Yue;
- Huang, Yimin;
- Zhu, Kaichuan;
- Zeng, Fan;
- Zhao, Junyi;
- Zhang, Huaqiu;
- Zhu, Xinzhou;
- Kettenmann, Helmut;
- Xiang, Xianyuan
Publication type:
Article
Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation.
Published in:
Theranostics, 2021, v. 11, n. 18, p. 8964, doi. 10.7150/thno.64022
By:
- Biechele, Gloria;
- Blume, Tanja;
- Deussing, Maximilian;
- Zott, Benedikt;
- Yuan Shi;
- Xianyuan Xiang;
- Franzmeier, Nicolai;
- Kleinberger, Gernot;
- Peters, Finn;
- Ochs, Katharina;
- Focke, Carola;
- Sacher, Christian;
- Wind, Karin;
- Schmidt, Claudio;
- Lindner, Simon;
- Gildehaus, Franz-Josef;
- Eckenweber, Florian;
- Beyer, Leonie;
- von Ungern-Sternberg, Barbara;
- Bartenstein, Peter
Publication type:
Article
Response to Comment on "Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases".
Published in:
Science Translational Medicine, 2022, v. 14, n. 659, p. 1, doi. 10.1126/scitranslmed.abn5104
By:
- Xiang, Xianyuan;
- Tahirovic, Sabina;
- Ziegler, Sibylle;
- Haass, Christian;
- Brendel, Matthias
Publication type:
Article
Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases.
Published in:
Science Translational Medicine, 2021, v. 13, n. 615, p. 1, doi. 10.1126/scitranslmed.abe5640
By:
- Xiang, Xianyuan;
- Wind, Karin;
- Wiedemann, Thomas;
- Blume, Tanja;
- Shi, Yuan;
- Briel, Nils;
- Beyer, Leonie;
- Biechele, Gloria;
- Eckenweber, Florian;
- Zatcepin, Artem;
- Lammich, Sven;
- Ribicic, Sara;
- Tahirovic, Sabina;
- Willem, Michael;
- Deussing, Maximilian;
- Palleis, Carla;
- Rauchmann, Boris-Stephan;
- Gildehaus, Franz-Josef;
- Lindner, Simon;
- Spitz, Charlotte
Publication type:
Article
Versatile strategies for adult neurogenesis: avenues to repair the injured brain.
Published in:
Neural Regeneration Research, 2024, v. 19, n. 4, p. 774, doi. 10.4103/1673-5374.382224
By:
- Junyi Zhao;
- Siyu Liu;
- Xianyuan Xiang;
- Xinzhou Zhu
Publication type:
Article
Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer's disease.
Published in:
Molecular Neurodegeneration, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13024-024-00752-6
By:
- Zatcepin, Artem;
- Gnörich, Johannes;
- Rauchmann, Boris-Stephan;
- Bartos, Laura M.;
- Wagner, Stephan;
- Franzmeier, Nicolai;
- Malpetti, Maura;
- Xiang, Xianyuan;
- Shi, Yuan;
- Parhizkar, Samira;
- Grosch, Maximilian;
- Wind-Mark, Karin;
- Kunte, Sebastian T.;
- Beyer, Leonie;
- Meyer, Carolin;
- Brösamle, Desirée;
- Wendeln, Ann-Christin;
- Osei-Sarpong, Collins;
- Heindl, Steffanie;
- Liesz, Arthur
Publication type:
Article
The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions.
Published in:
Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00402-7
By:
- Takalo, Mari;
- Wittrahm, Rebekka;
- Wefers, Benedikt;
- Parhizkar, Samira;
- Jokivarsi, Kimmo;
- Kuulasmaa, Teemu;
- Mäkinen, Petra;
- Martiskainen, Henna;
- Wurst, Wolfgang;
- Xiang, Xianyuan;
- Marttinen, Mikael;
- Poutiainen, Pekka;
- Haapasalo, Annakaisa;
- Hiltunen, Mikko;
- Haass, Christian
Publication type:
Article
The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
Published in:
Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0280-6
By:
- Xiang, Xianyuan;
- Piers, Thomas M.;
- Wefers, Benedikt;
- Zhu, Kaichuan;
- Mallach, Anna;
- Brunner, Bettina;
- Kleinberger, Gernot;
- Song, Wilbur;
- Colonna, Marco;
- Herms, Jochen;
- Wurst, Wolfgang;
- Pocock, Jennifer M.;
- Haass, Christian
Publication type:
Article

Found: 17