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- Title
Bacterial virulence phenotypes of Escherichia coli and host susceptibility determine risk for urinary tract infections.
- Authors
Schreiber IV, Henry L.; Conover, Matt S.; Wen-Chi Chou; Hibbing, Michael E.; Manson, Abigail L.; Dodson, Karen W.; Hannan, Thomas J.; Roberts, Pacita L.; Stapleton, Ann E.; Hooton, Thomas M.; Livny, Jonathan; Earl, Ashlee M.; Hultgren, Scott J.
- Abstract
The article presents an analysis on the bacterial virulence phenotypes of Escherichia coli and host susceptibility, in determining the risk for urinary tract infections (UTIs). It examines the genetically diverse and urovirulence of bacterial virulence in Escherichia coli and its putative urovirulence factors (PUFs). The findings also suggests that UTI risk may be determined by complex interactions between bacterial strains and host susceptibility.
- Subjects
MICROBIAL virulence; URINARY tract infections; ESCHERICHIA coli; ESCHERICHIA coli toxins; URINARY tract infection diagnosis
- Publication
Science Translational Medicine, 2017, Vol 9, Issue 382, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aaf1283