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- Title
Osteoarthritis and chronic pain: Interleukin-6 as a common denominator and therapeutic target.
- Authors
Pacifici, Maurizio
- Abstract
Osteoarthritis (OA) is a common and problematic disorder that is often associated with chronic pain, a combination that renders OA a leading cause of physical disability and an unmet clinical challenge. In this issue of Science Signaling, Liao et al. show that interleukin-6 is a driver of both joint tissue degradation and pain, revealing a common culprit and a possible comprehensive target of therapeutic intervention.
- Subjects
CHRONIC pain; INTERLEUKIN-6; OSTEOARTHRITIS; DISABILITIES
- Publication
Science Signaling, 2022, Vol 15, Issue 744, p1
- ISSN
1945-0877
- Publication type
Article
- DOI
10.1126/scisignal.add3702