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- Title
Factores relacionados con histoplasmosis diseminada en los pacientes admitidos con VIH-SIDA y fiebre, CHDrAAM, 2017 - 2019.
- Authors
González Rodriguéz, José Anel; Chérigo, Elam; Gundacker, Nathan; Antonio Suárez, José
- Abstract
Introduction: The diagnosis of disseminated histoplasmosis (HD) is a challenge due to the similarity of the clinical picture with other infectious and non-infectious diseases. Confirming a case of HD requires performing insensitive procedures such as blood cultures, myelocultures and tissue biopsies, or expensive procedures such as urinary Histoplasma capsulatum antigen. Knowing the clinical and laboratory factors related to the diagnosis of HD is of vital importance, especially in places with limited resources. Methodology: a retrospective cohort study was conducted where clinical records of patients with fever and HIV-AIDS, admitted with suspected disseminated histoplasmosis from January 1, 2017, to December 31, 2019, at the Complejo Hospitalario Dr. Arnulfo Arias Madrid (CHDrAAM) in Panama, were evaluated for demographic, clinical and laboratory characteristics related to the diagnosis of HD. Results: 63 patients met the inclusion criteria, 14 with confirmed diagnosis of HD and 49 with unconfirmed diagnosis of HD. Lactate dehydrogenase (LDH) and aspartate transaminase (AST) levels were related to HD diagnosis in univariate analysis. After logistic regression neither AST nor LDH were statistically significant. (p= 0.22 and P = 0.92). Conclusion: No clinical or laboratory characteristics were independently related to the diagnosis of HD in HIV-AIDS patients admitted with suspected disseminated histoplasmosis.
- Publication
Revista Médica de Panamá, 2021, Issue 3, p42
- ISSN
0379-1629
- Publication type
Article
- DOI
10.37980/im.journal.rmdp.20211820