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- Title
Beneficial Effects of Long-Term CPAP Treatment on Sleep Quality and Blood Pressure in Adherent Subjects With Obstructive Sleep Apnea.
- Authors
Mei-Chen Yang; Yi-Chih Huang; Chou-Chin Lan; Yao-Kuang Wu; Kuo-Feng Huang
- Abstract
BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular diseases. Although CPAP is the first treatment choice for moderate-to-severe OSA, acceptance of and adherence to CPAP remain problematic. High CPAP adherence is generally defined as ≥4 h of use/night for ≥70% of the nights monitored. We investigated the long-term beneficial effects of CPAP on sleep quality and blood pressure in subjects with moderate-to-sevcrc OSA according to high or low CPAP adherence. METHODS: We retrospectively analyzed 121 subjects with moderate-to-severe OSA from August 2008 to July 2012. These subjects were divided into 3 groups: (1) no CPAP treatment (n = 29), (2) low CPAP adherence (n = 28), and (3) high CPAP adherence (n = 64). All subjects were followed up for at least 1 y. The 3 groups were compared regarding anthro-pometric and polysomnographic variables, presence of cardiovascular comorbidities, and blood pressure at baseline and at the last follow-up. RESULTS: The no-treatment group showed significant increases in oxygen desaturation index and blood pressure. The high-adherence group showed significant improvement in daytime sleepiness, apnea-hypopnea index (AHI), oxygen desaturation index, and blood pressure. Although the AHI was also significantly decreased after CPAP treatment in the low-adherence group, blood pressure remained unchanged. CONCLUSIONS: CPAP treatment had beneficial effects on both sleep quality and blood pressure only in subjects with OSA and high CPAP adherence who used CPAP for ≥4 h/night for ≥70% of nights monitored. Subjects with low CPAP adherence received beneficial effects on AHI, but not blood pressure.
- Subjects
SLEEP apnea syndrome treatment; ANTHROPOMETRY; BLOOD pressure measurement; CARDIOVASCULAR diseases risk factors; PATIENT compliance; PROBABILITY theory; QUALITY assurance; SLEEP; SLEEP apnea syndromes; POLYSOMNOGRAPHY; RETROSPECTIVE studies; CONTINUOUS positive airway pressure; DATA analysis software; DESCRIPTIVE statistics; DISEASE complications
- Publication
Respiratory Care, 2015, Vol 60, Issue 12, p1810
- ISSN
0020-1324
- Publication type
Article
- DOI
10.4187/respcare.04199