We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Early, Real-Time Medical Diagnosis of Botulism by Endopeptidase-Mass Spectrometry.
- Authors
Rosen, Osnat; Feldberg, Liron; Gura, Sigalit; Brosh-Nissimov, Tal; Guri, Alex; Zimhony, Oren; Shapiro, Eli; Beth-Din, Adi; Stein, Dana; Ozeri, Eyal; Barnea, Ada; Turgeman, Amram; Ben David, Alon; Schwartz, Arieh; Elhanany, Eytan; Diamant, Eran; Yitzhaki, Shmuel; Zichel, Ran
- Abstract
Botulinum toxin was detected in patient serum using Endopeptidase- mass-spectrometry assay, although all conventional tests provided negative results. Antitoxin was administered, resulting in patient improvement. Implementing this highly sensitive and rapid assay will improve preparedness for foodborne botulism and deliberate exposure.
- Subjects
BOTULISM diagnosis; ENDOPEPTIDASES; MASS spectrometry; ANTITOXINS; DRUG administration; THERAPEUTICS
- Publication
Clinical Infectious Diseases, 2015, Vol 61, Issue 12, pe58
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/civ861