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- Title
The Antimicrobial Resistance Monitoring and Research (ARMoR) Program: The US Department of Defense Response to Escalating Antimicrobial Resistance.
- Authors
Lesho, Emil P.; Waterman, Paige E.; Chukwuma, Uzo; McAuliffe, Kathryn; Neumann, Charlotte; Julius, Michael D.; Crouch, Helen; Chandrasekera, Ruvani; English, Judith F.; Clifford, Robert J.; Kester, Kent E.
- Abstract
We describe an integrated program comprised of infection preventionists, enterprise-wide surveillance mandates, centralized laboratory characterization with molecular diagnostics and bioinformatics, electronic medical record data mining, feedback to stakeholders, and applied research. Certain types of antimicrobial resistance decreased after program inception.Responding to escalating antimicrobial resistance (AMR), the US Department of Defense implemented an enterprise-wide collaboration, the Antimicrobial Resistance Monitoring and Research Program, to aid in infection prevention and control. It consists of a network of epidemiologists, bioinformaticists, microbiology researchers, policy makers, hospital-based infection preventionists, and healthcare providers who collaborate to collect relevant AMR data, conduct centralized molecular characterization, and use AMR characterization feedback to implement appropriate infection prevention and control measures and influence policy. A particularly concerning type of AMR, carbapenem-resistant Enterobacteriaceae, significantly declined after the program was launched. Similarly, there have been no further reports or outbreaks of another concerning type of AMR, colistin resistance in Acinetobacter, in the Department of Defense since the program was initiated. However, bacteria containing AMR-encoding genes are increasing. To update program stakeholders and other healthcare systems facing such challenges, we describe the processes and impact of the program.
- Subjects
BACTERIAL disease prevention; ANTI-infective agents; DRUG resistance in microorganisms; MOLECULAR diagnosis; BIOINFORMATICS; ELECTRONIC health records
- Publication
Clinical Infectious Diseases, 2014, Vol 59, Issue 3, p390
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciu319