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- Title
Comparison of Central Corneal Thickness Measurement Using Ultrasound Pachymetry and Current Diagnostic Devices in Normal and Keratoconic Eyes.
- Authors
ÜNLÜ, Metin; AKÇAM, Hanife Tuba; YÜKSEL, Erdem; HONDUR, Ahmet Murad
- Abstract
Aim: To compare central corneal thickness (CCT) measurements using four different imaging systems in normal and keratoconic eyes. Methods: In this retrospective study, a total of 92 eyes of 92 patients (53 normal eyes, 39 keratoconus eyes) were included. Five consecutive measurements were taken with optical low-coherence reflectometry (OLCR), Scheimpflug-Placido Topographer, spectral domain optical coherence tomography (SD-OCT), and ultrasound pachymetry (USP). Results: In normal eyes, mean OLCR, Scheimpflug-Placido Topographer, SD-OCT, and USP CCT measurements were 520.76±4.31 µm, 519.96±4.33 µm, 522.40±4.20 µm, and 528.89±4.11 µm respectively. There was a statistically significant difference in the CCT measurements between the OLCR and USP and the Scheimpflug-Placido Topographer and USP (p=0.003, p=0.01 respectively). All four modalities of CCT measurements correlated closely with each other, with Pearson correlation coefficients ranging from 0.957 to 0.983. In keratoconic eyes, average OLCR, Scheimpflug-Placido Topographer, SD-OCT, and USP CCT measurements were 449.93±5.77 µm, 455.48±5.79 µm, 457.21±5.61 µm, and 465.87±5.49 µm respectively. In keratoconic eyes, OLCR measurements were thinner than those of USP by a mean of 15.93 µm, of SD-OCT by an average of 7.27 µm (p<0.001, and p=0.007 respectively). All 4 modalities of CCT measurements correlated closely with each other, with Pearson correlation coefficients ranging from 0.872 to 0.932. Conclusion: Scheimpflug-Placido Topographer and SD-OCT measurements showed good agreement with ultrasound pachymetry in normal and keratoconic eyes. However, OLCR measurements were thinner than the other three devices in keratoconic eyes. Scheimpfl ug-Placido Topographer, USP, SD-OCT, and OLCR should not be used interchangeably in keratoconic eyes.
- Subjects
CORNEA; CORNEA diseases; KERATOCONUS; EYE diseases; PEARSON correlation (Statistics)
- Publication
Journal of Glaucoma-Cataract / Glokom-Katarakt, 2017, Vol 12, Issue 2, p98
- ISSN
1305-9173
- Publication type
Article