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- Title
Physical Activity in the Prevention of Type 2 Diabetes.
- Authors
Laaksonen, David E.; Lindström, Jaana; Lakka, Timo A.; Eriksson, Johan G.; Niskanen, Leo; Wikström, Katja; Aunola, Sirkka; Keinänen-Kiukaanniemi, Sirkka; Laakso, Mauri; Valle, Timo T.; Ilanne-Parikka, Pirjo; Louheranta, Anne; Hämäläinen, Helena; Rastas, Merja; Salminen, Virpi; Cepaitis, Zygimantas; Hakumäki, Martti; Kaikkonen, Hannu; Härkönen, Pirjo; Sundvall, Jouko
- Abstract
Clinical trials have demonstrated that lifestyle changes can prevent type 2 diabetes, but the importance of leisure-time physical activity (LTPA) is still unclear. We carried out post hoc analyses on the role of LTPA in preventing type 2 diabetes in 487 men and women with impaired glucose tolerance who had completed 12-month LTPA questionnaires. The subjects were participants in the Finnish Diabetes Prevention Study, a randomized controlled trial of lifestyle changes including diet, weight loss, and LTPA. There were 107 new cases of diabetes during the 4.1-year follow-up period. Individuals who increased moderate-to-vigorous LTPA or strenuous, structured LTPA the most were 63-65% less likely to develop diabetes. Adjustment for changes in diet and body weight during the study attenuated the association somewhat (upper versus lower third: moderate-to-vigorous LTPA, relative risk 0.51, 95% CI 0.26-0.97; strenuous, structured LTPA, 0.63, 0.35-1.13). Low-intensity and lifestyle LTPA and walking also conferred benefits, consistent with the finding that the change in total LTPA (upper versus lower third: 0.34, 0.19-0.62) was the most strongly associated with incident diabetes. Thus increasing physical activity may substantially reduce the incidence of type 2 diabetes in high-risk individuals. Diabetes 54:158-165, 2005
- Subjects
TYPE 2 diabetes prevention; LIFESTYLES; GLUCOSE; DIET; WEIGHT loss
- Publication
Diabetes, 2005, Vol 54, Issue 1, p158
- ISSN
0012-1797
- Publication type
Article