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- Title
Sensory Involvement in Amyotrophic Lateral Sclerosis.
- Authors
Rubio, Miguel A.; Herrando-Grabulosa, Mireia; Navarro, Xavier
- Abstract
Although amyotrophic lateral sclerosis (ALS) is pre-eminently a motor disease, the existence of non-motor manifestations, including sensory involvement, has been described in the last few years. Although from a clinical perspective, sensory symptoms are overshadowed by their motor manifestations, this does not mean that their pathological significance is not relevant. In this review, we have made an extensive description of the involvement of sensory and autonomic systems described to date in ALS, from clinical, neurophysiological, neuroimaging, neuropathological, functional, and molecular perspectives.
- Subjects
MOTOR neuron diseases; AMYOTROPHIC lateral sclerosis; BRAIN imaging
- Publication
International Journal of Molecular Sciences, 2022, Vol 23, Issue 24, p15521
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms232415521