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- Title
Highlighting Immune System and Stress in Major Depressive Disorder, Parkinson's, and Alzheimer's Diseases, with a Connection with Serotonin.
- Authors
Correia, Ana Salomé; Cardoso, Armando; Vale, Nuno
- Abstract
There is recognition that both stress and immune responses are important factors in a variety of neurological disorders. Moreover, there is an important role of several neurotransmitters that connect these factors to several neurological diseases, with a special focus in this paper on serotonin. Accordingly, it is known that imbalances in stressors can promote a variety of neuropsychiatric or neurodegenerative pathologies. Here, we discuss some facts that link major depressive disorder, Alzheimer's, and Parkinson's to the stress and immune responses, as well as the connection between these responses and serotonergic signaling. These are important topics of investigation which may lead to new or better treatments, improving the life quality of patients that suffer from these conditions.
- Subjects
MENTAL depression; ALZHEIMER'S disease; SEROTONIN; IMMUNE system; DULOXETINE; NEUROLOGICAL disorders; NEUROTRANSMITTERS
- Publication
International Journal of Molecular Sciences, 2021, Vol 22, Issue 16, p8525
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms22168525