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- Title
Recent Advances in Synthetic Bioelastomers.
- Authors
Rui Shi; Dafu Chen; Quanyong Liu; Yan Wu; Xiaochuan Xu; Liqun Zhang; Wei Tian
- Abstract
This article reviews the degradability of chemically synthesized bioelastomers, mainly designed for soft tissue repair. These bioelastomers involve biodegradable polyurethanes, polyphosphazenes, linear and crosslinked poly(ether/ester)s, poly(ϵ-caprolactone) copolymers, poly(1,3-trimethylene carbonate) and their copolymers, poly(polyol sebacate)s, poly(diol-citrates) and poly(ester amide)s. The in vitro and in vivo degradation mechanisms and impact factors influencing degradation behaviors are discussed. In addition, the molecular designs, synthesis methods, structure properties, mechanical properties, biocompatibility and potential applications of these bioelastomers were also presented.
- Subjects
METAPLASTIC ossification; SOFT tissue injuries; CONDUCTING polymers; BIOSYNTHESIS; BIOCOMPATIBILITY; POLYURETHANES; BIOMEDICAL materials; COPOLYMERS; POLYETHERS
- Publication
International Journal of Molecular Sciences, 2009, Vol 10, Issue 10, p4223
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms10104223