We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Early neurodevelopmental outcome of low birth weight infants surviving neonatal intraventricular hemorrhage.
- Authors
Williamson, W. Daniel; Desmond, Murdina M.; Wilson, Geraldine S.; Andrew, Leora; Garcia-Prats, Joseph A.
- Abstract
This article reports the follow-up findings in 28 pre-term infants who survived symptomatic neonatal intraventricular hemorrhage and were cared for in the Neonatal Intensive Care Unit of Texas Children's Hospital, Houston. The severity of hemorrhage noted on CT scan was graded using the system of PAPILE, et al. [2]. The mean gestational age for the group was 28.9 weeks (range 25 to 35 weeks) and mean birth weight was 1,179 grams (range 700 to 1,930 grams). Seventeen infants were male and eleven were female. Paternal social class (HOLLINGSHEAD's classification) was distributed as follows: 27% class II, 31% class III, and 42% class IV. Follow-up consisted of neurologic examination and multidisciplinary developmental assessment. The outcome categorizations (normal, suspect, abnormal) were based on both neurologic and developmental functioning. A child considered "normal" had a normal neurologic examination and developmental function within the normal range for corrected age. The term "multihandi-capped" indicated both significant developmental delay and abnormal neurologic findings. At a mean age of 19.7 months, five infants were considered normal (18%), eight suspect (28%), and fifteen abnormal (54%). (Tab. II). Eight abnormal infants were multihandicapped. Cerebral palsy was noted in nine infants (32%). (Tab. I). Post-hemorrhagic hydrocephalus was noted in eight; seven required shunting. Three infants with shunts later demonstrated microcephaly. (Fig. 1). Three developed infantile spasms. Neurosensory deficits included blindness (secondary to cicatricial retinopathy of prematurity) in four infants and hearing loss in two. At least one-third of the study group will require special education by age three years. Two significant findings emerged in this study. First, the incidence of abnormal outcome was higher among infants with Grades III and IV hemorrhage (79%) than among infants with Grades I or II hemorrhage (29%) (.OK P < .025). Second, the mean gestational age of the eight multihandicapped infants (27.0 weeks) was significantly below that of the remaining twenty infants (29.7 weeks) (.001 < P < .01). Although forty-six percent of the study group did not have static abnormalities when evaluated, they remain at risk for disorders of language, teaming and behavior. Longterm follow-up öf these infants is planned to determine if these disorders may, in part, be related to the occurrence or secondary effects of earlier intraventricular hemorrhage.
- Publication
Journal of Perinatal Medicine, 1982, Vol 10, Issue 1, p34
- ISSN
0300-5577
- Publication type
Article