We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Cardiac sympathetic denervation in Parkinson’s disease linked to SNCA duplication.
- Authors
Orimo, Satoshi; Uchihara, Toshiki; Nakamura, Ayako; Mori, Fumiaki; Ikeuchi, Takeshi; Onodera, Osamu; Nishizawa, Masatoyo; Ishikawa, Atsushi; Kakita, Akiyoshi; Wakabayashi, Koichi; Takahashi, Hitoshi
- Abstract
The article focuses on a study which found out that cardiac sympathetic denervation is closely related to the presence of Lewy bodies. The study states that the relationship is not only in sporadic Lewy body disorders but also in familial Parkinson's disease (PD) with different mutations of SNCA duplication. In addition, the reduced cardiac uptake of meta-iodobenzylguanidine or Xuorodopamine is a potential biomarker for the presence of Lewy bodies not only in sporadic but also in familial PD.
- Subjects
HEART diseases; NEUROSURGERY; LEWY body dementia; PARKINSON'S disease; BRAIN diseases
- Publication
Acta Neuropathologica, 2008, Vol 116, Issue 5, p575
- ISSN
0001-6322
- Publication type
Letter
- DOI
10.1007/s00401-008-0428-5