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Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1.
Published in:
2016
By:
- Henninger, Nils;
- Bouley, James;
- Sikoglu, Elif M.;
- An, Jiyan;
- Moore, Constance M.;
- King, Jean A.;
- Bowser, Robert;
- Freeman, Marc R.;
- Brown Jr, Robert H.;
- Brown, Robert H Jr
Publication type:
journal article
Targeted mutation of mouse skeletal muscle sodium channel produces myotonia and potassium-sensitive weakness.
Published in:
2008
By:
- Hayward, Lawrence J.;
- Kim, Joanna S.;
- Ming-Yang Lee;
- Hongru Zhou;
- Kim, Ji W.;
- Misra, Kumudini;
- Salajegheh, Mohammad;
- Fen-fen Wu;
- Matsuda, Chie;
- Reid, Valerie;
- Cros, Didier;
- Hoffman, Eric P.;
- Renaud, Jean-Marc;
- Cannon, Stephen C.;
- Brown Jr., Robert H.;
- Lee, Ming-Yang;
- Zhou, Hongru;
- Wu, Fen-fen;
- Brown, Robert H Jr
Publication type:
journal article
Analysis of a genetic defect in the TATA box of the SOD1 gene in a patient with familial amyotrophic lateral sclerosis.
Published in:
2007
By:
- Niemann, Stephan;
- Broom, Wendy J.;
- Brown Jr., Robert H.;
- Brown, Robert H Jr
Publication type:
journal article
Comparison of incremental with multipoint MUNE methods in transgenic ALS mice.
Published in:
2002
By:
- Shefner, Jeremy M.;
- Cudkowicz, Merit E.;
- Brown, Robert H.;
- Brown, Robert H Jr
Publication type:
journal article
Emerging mechanisms of molecular pathology in ALS.
Published in:
2015
By:
- Peters, Owen M;
- Ghasemi, Mehdi;
- Brown Jr, Robert H;
- Brown, Robert H Jr
Publication type:
journal article
Amyotrophic Lateral Sclerosis: Fuel for the Corticofugal Feud.
Published in:
2020
By:
- Wainger, Brian J.;
- Brown, Robert H.;
- Brown, Robert H Jr
Publication type:
journal article
A novel, blood-based diagnostic assay for limb girdle muscular dystrophy 2B and Miyoshi myopathy.
Published in:
2002
By:
- Ho, Mengfatt;
- Gallardo, Eduard;
- McKenna-Yasek, Diane;
- De Luna, Noemi;
- Illa, Isabel;
- Brown Jr., Robert H.;
- Brown, Robert H Jr
Publication type:
journal article
Irreversible reduction in potassium fluxes accompanies terminal differentiation of human myoblasts to myotubes.
Published in:
Journal of Cellular Physiology, 1987, v. 132, n. 1, p. 57, doi. 10.1002/jcp.1041320108
By:
- Panet, Rivka;
- Digregorio, Debra M.;
- Brown, Robert H.
Publication type:
Article
TREATMENT OF ACNE VULGARIS: COMBINATION OF 3% ERYTHROMYCIN AND 5% BENZOYL PEROXIDE IN A GEL COMPARED TO CLINDAMYCIN PHOSPHATE LOTION.
Published in:
International Journal of Dermatology, 1996, v. 35, n. 3, p. 209, doi. 10.1111/j.1365-4362.1996.tb01644.x
By:
- Packman, Albert M.;
- Brown, Robert H.;
- Dunlap, Frank E.;
- Kraus, Stephen J.;
- Webster, Guy F.
Publication type:
Article
Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30387-4
By:
- Krishnan, Gopinath;
- Raitcheva, Denitza;
- Bartlett, Daniel;
- Prudencio, Mercedes;
- McKenna-Yasek, Diane M.;
- Douthwright, Catherine;
- Oskarsson, Björn E.;
- Ladha, Shafeeq;
- King, Oliver D.;
- Barmada, Sami J.;
- Miller, Timothy M.;
- Bowser, Robert;
- Watts, Jonathan K.;
- Petrucelli, Leonard;
- Brown, Robert H.;
- Kankel, Mark W.;
- Gao, Fen-Biao
Publication type:
Article
Cassini VIMS observations of H3+ emission on the nightside of Jupiter.
Published in:
Journal of Geophysical Research. Space Physics, 2015, v. 120, n. 8, p. 6948, doi. 10.1002/2015JA021097
By:
- Stallard, Tom S.;
- Melin, Henrik;
- Miller, Steve;
- Badman, Sarah V.;
- Baines, Kevin H.;
- Brown, Robert H.;
- Blake, James S. D.;
- O'Donoghue, James;
- Johnson, Rosie E.;
- Bools, Bethany;
- Pilkington, Nathan M.;
- East, Oliver T.L.;
- Fletcher, Mark
Publication type:
Article
Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22.
Published in:
2000
By:
- Hosler, Betsy A.;
- Siddique, Teepu;
- Sapp, Peter C.;
- Sailor, Wen;
- Huang, Michael C.;
- Hossain, Anwar;
- Daube, Jasper R.;
- Nance, Martha;
- Fan, Chaohong;
- Kaplan, Jocelyn;
- Hung, Wu-Yen;
- McKenna-Yasek, Diane;
- Haines, Jonathan L.;
- Pericak-Vance, Margaret A.;
- Horvitz, H. Robert;
- Brown Jr., Robert H.;
- Hosler, B A;
- Siddique, T;
- Sapp, P C;
- Sailor, W
Publication type:
journal article
Repeated mild traumatic brain injury triggers pathology in asymptomatic C9ORF72 transgenic mice.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 12, p. 5139, doi. 10.1093/brain/awad264
By:
- Kahriman, Aydan;
- Bouley, James;
- Tuncali, Idil;
- Dogan, Elif O;
- Pereira, Mariana;
- Luu, Thuyvan;
- Bosco, Daryl A;
- Jaber, Samer;
- Peters, Owen M;
- Brown, Robert H;
- Henninger, Nils
Publication type:
Article
SOD1 aggregates in ALS: Cause, correlate or consequence?
Published in:
Nature Medicine, 1998, v. 4, n. 12, p. 1362, doi. 10.1038/3945
By:
- Brown, Robert H.
Publication type:
Article
Prophylactic Creatine Administration Mediates Neuroprotection in Cerebral Ischemia in Mice.
Published in:
Journal of Neuroscience, 2004, v. 24, n. 26, p. 5909, doi. 10.1523/JNEUROSCI.1278-04.2004
By:
- Shan Zhu;
- Mingwei Li;
- Figueroa, Bryan E.;
- Aijian Liu;
- Stavrovskaya, Irina G.;
- Pasinelli, Piera;
- Beal, M. Flint;
- Brown Jr., Robert H.;
- Kristal, Bruce S.;
- Ferrante, Robert J.;
- Friedlander, Robert M.
Publication type:
Article
O4‐05‐02: THE INVESTIGATIONAL STEREOPURE ANTISENSE OLIGONUCLEOTIDE WVE‐3972‐01 PREFERENTIALLY REDUCES G4C2 REPEAT‐CONTAINING C9ORF72 TRANSCRIPTS: A POTENTIAL THERAPEUTIC APPROACH FOR THE TREATMENT OF FRONTOTEMPORAL DEMENTIA
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1411, doi. 10.1016/j.jalz.2018.06.2934
By:
- Dodart, Jean-Cosme;
- Liu, Yuanjing;
- Tran, Helene;
- Berkovitch, Shaunna;
- Byrne, Michael;
- Durbin, Ann;
- Iwamoto, Naoki;
- Jang, Hyun Gyung;
- Kandasamy, Pachamuthu;
- Liu, Fangjun;
- Mohapatra, Susovan;
- Yang, Hailin;
- Yin, Yuan;
- Zhang, Jason;
- Zhong, Zhong;
- Vargeese, Chandra;
- Brown, Robert H.
Publication type:
Article
Anti-SOD1 Nanobodies That Stabilize Misfolded SOD1 Proteins Also Promote Neurite Outgrowth in Mutant SOD1 Human Neurons.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 16013, doi. 10.3390/ijms232416013
By:
- Kumar, Meenakshi Sundaram;
- Fowler-Magaw, Megan E.;
- Kulick, Daniel;
- Boopathy, Sivakumar;
- Gadd, Del Hayden;
- Rotunno, Melissa;
- Douthwright, Catherine;
- Golebiowski, Diane;
- Yusuf, Issa;
- Xu, Zuoshang;
- Brown Jr., Robert H.;
- Sena-Esteves, Miguel;
- O'Neil, Alison L.;
- Bosco, Daryl A.
Publication type:
Article
Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1.
Published in:
2011
By:
- Garofalo, Kevin;
- Penno, Anke;
- Schmidt, Brian P.;
- Lee, Ho-Joon;
- Frosch, Matthew P.;
- von Eckardstein, Arnold;
- Brown, Robert H.;
- Hornemann, Thorsten;
- Eichler, Florian S.
Publication type:
journal article
Ion Channel Mutations in Periodic Paralysis and Related Myotonic Diseasesa.
Published in:
Annals of the New York Academy of Sciences, 1993, v. 707, n. 1, p. 305, doi. 10.1111/j.1749-6632.1993.tb38061.x
By:
- BROWN, ROBERT H.
Publication type:
Article
Polyubiquitin Gene Expression following Cerebral Ischemiaa.
Published in:
Annals of the New York Academy of Sciences, 1993, v. 679, n. 1, p. 188, doi. 10.1111/j.1749-6632.1993.tb18298.x
By:
- CADAY, CORNELIO G.;
- SKLAR, ROBERT M.;
- BERLOVE, DAVID J.;
- KEMMOU, AHMED;
- BROWN, ROBERT H.;
- FINKLESTEIN, SETH P.
Publication type:
Article
Human Immunodeficiency Virus-associated Chronic Obstructive Pulmonary Disease Is Characterized by Increased Small Airways Dysfunction on Computed Tomography Imaging.
Published in:
Annals of the American Thoracic Society, 2023, v. 20, n. 2, p. 335, doi. 10.1513/annalsats.202203-203rl
By:
- Raju, Sarath;
- Gearhart, Andrew S.;
- Drummond, M. Bradley;
- Brown, Nicole;
- Ramamurthi, Hema C.;
- Kirk, Gregory D.;
- Brown, Robert H.;
- McCormack, Meredith C.
Publication type:
Article
Lung Function and Respiratory Symptoms after Tuberculosis in an American Indian Population. The Strong Heart Study.
Published in:
2020
By:
- Powers, Martha;
- Sanchez, Tiffany R.;
- Welty, Thomas K.;
- Cole, Shelley A.;
- Oelsner, Elizabeth C.;
- Yeh, Fawn;
- Turner, Joanne;
- O'Leary, Marcia;
- Brown, Robert H.;
- O'Donnell, Max;
- Lederer, David;
- Navas-Acien, Ana
Publication type:
journal article
Obstructive Sleep Apnea and Airway Dimensions in Chronic Obstructive Pulmonary Disease.
Published in:
2020
By:
- Koch, Abigail L.;
- Brown, Robert H.;
- Woo, Han;
- Brooker, Alli C.;
- Paulin, Laura M.;
- Schneider, Hartmut;
- Schwartz, Alan R.;
- Diette, Gregory B.;
- Wise, Robert A.;
- Hansel, Nadia N.;
- Putcha, Nirupama
Publication type:
Letter
Individual Canine Airway Response Variability to a Deep Inspiration.
Published in:
Clinical Medicine Insights: Circulatory, Respiratory & Pulmonary Medicine, 2011, n. 5, p. 7, doi. 10.4137/CCRPM.S6531
By:
- Brown, Robert H.;
- Kaczka, David W.;
- Fallano, Katherine;
- Shapiro, Steve;
- Mitzner, Wayne
Publication type:
Article
Putting the heat on ALS.
Published in:
Nature Medicine, 2004, v. 10, n. 4, p. 345, doi. 10.1038/nm0404-345
By:
- Benn, Susanna C.;
- Brown, Robert H.
Publication type:
Article
Administering pharmaceuticals to latex-allergic patients from vials containing natural rubber latex closures.
Published in:
American Journal of Health-System Pharmacy, 2005, v. 62, n. 17, p. 1822, doi. 10.2146/ajhp050021
By:
- Hamilton, Robert G.;
- Brown, Robert H.;
- Veltri, Michael A.;
- Feroli, E. Robert;
- Primeau, Marie Noel;
- Schauble, James F.;
- Adkinson Jr., N. Franklin
Publication type:
Article
ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis.
Published in:
Nature Genetics, 2006, v. 38, n. 4, p. 411, doi. 10.1038/ng1742
By:
- Greenway, Matthew J.;
- Andersen, Peter M.;
- Russ, Carsten;
- Ennis, Sean;
- Cashman, Susan;
- Donaghy, Colette;
- Patterson, Victor;
- Swingler, Robert;
- Kieran, Dairin;
- Prehn, Jochen;
- Morrison, Karen E.;
- Green, Andrew;
- Acharya, K. Ravi;
- Brown Jr., Robert H.;
- Hardiman, Orla
Publication type:
Article
Mutant dynactin in motor neuron disease.
Published in:
Nature Genetics, 2003, v. 33, n. 4, p. 455, doi. 10.1038/ng1123
By:
- Puls, Imke;
- Jonnakuty, Catherine;
- LaMonte, Bernadette H.;
- Holzbaur, Erika L.F.;
- Tokito, Mariko;
- Mann, Eric;
- Floeter, Mary Kay;
- Bidus, Kimberly;
- Drayna, Dennis;
- Oh, Shin J.;
- Brown, Robert H.;
- Ludlow, Christy L.;
- Fischbeck, Kenneth H.
Publication type:
Article
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.
Published in:
Nature Genetics, 2001, v. 29, n. 2, p. 166, doi. 10.1038/ng1001-166
By:
- Hadano, Shinji;
- Hand, Collette K.;
- Osuga, Hitoshi;
- Yanagisawa, Yoshiko;
- Otomo, Asako;
- Devon, Rebecca S.;
- Miyamoto, Natsuki;
- Showguchi-Miyata, Junko;
- Okada, Yoshinori;
- Singaraja, Roshni;
- Figlewicz, Denise A.;
- Kwiatkowski, Thomas;
- Hosler, Betsy A.;
- Sagie, Tally;
- Skaug, Jennifer;
- Nasir, Jamal;
- Brown, Robert H.;
- Scherer, Stephen W.;
- Rouleau, Guy A.
Publication type:
Article
SPTLC1 is mutated in hereditary sensory neuropathy, type 1.
Published in:
Nature Genetics, 2001, v. 27, n. 3, p. 261, doi. 10.1038/85817
By:
- Bejaoui, Khemissa;
- Wu, Chenyan;
- Scheffler, Margaret D.;
- Haan, Geoffry;
- Ashby, Peter;
- Wu, Lianchan;
- de Jong, Peter;
- Brown, Robert H.
Publication type:
Article
Observational Evidence for Summer Rainfall at Titan's North Pole.
Published in:
Geophysical Research Letters, 2019, v. 46, n. 3, p. 1205, doi. 10.1029/2018GL080943
By:
- Dhingra, Rajani D.;
- Barnes, Jason W.;
- Brown, Robert H.;
- Burrati, Bonnie J.;
- Sotin, Christophe;
- Nicholson, Phillip D.;
- Baines, Kevin H.;
- Clark, Roger N.;
- Soderblom, Jason M.;
- Jauman, Ralf;
- Rodriguez, Sebastien;
- Mouélic, Stéphane Le;
- Turtle, Elizabeth P.;
- Perry, Jason E.;
- Cottini, Valeria;
- Jennings, Don E.
Publication type:
Article
Specular reflection on Titan: Liquids in Kraken Mare.
Published in:
Geophysical Research Letters, 2010, v. 37, n. 7, p. n/a, doi. 10.1029/2009GL042312
By:
- Stephan, Katrin;
- Jaumann, Ralf;
- Brown, Robert H.;
- Soderblom, Jason M.;
- Soderblom, Laurence A.;
- Barnes, Jason W.;
- Sotin, Christophe;
- Griffith, Caitlin A.;
- Kirk, Randolph L.;
- Baines, Kevin H.;
- Buratti, Bonnie J.;
- Clark, Roger N.;
- Lytle, Dyer M.;
- Nelson, Robert M.;
- Nicholson, Phillip D.
Publication type:
Article
Stress among emergency medical staff: the US solution.
Published in:
Canadian Medical Association Journal (CMAJ), 1989, v. 140, n. 3, p. 262
By:
- Brown, Robert H.
Publication type:
Article
An epigenome-wide study of DNA methylation profiles and lung function among American Indians in the Strong Heart Study.
Published in:
Clinical Epigenetics, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13148-022-01294-8
By:
- Domingo-Relloso, Arce;
- Riffo-Campos, Angela L.;
- Powers, Martha;
- Tellez-Plaza, Maria;
- Haack, Karin;
- Brown, Robert H.;
- Umans, Jason G.;
- Fallin, M. Daniele;
- Cole, Shelley A.;
- Navas-Acien, Ana;
- Sanchez, Tiffany R.
Publication type:
Article
Inhibition of Fast Axonal Transport by Pathogenic SOD1 Involves Activation of p38 MAP Kinase.
Published in:
PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0065235
By:
- Morfini, Gerardo A.;
- Bosco, Daryl A.;
- Brown, Hannah;
- Gatto, Rodolfo;
- Kaminska, Agnieszka;
- Song, Yuyu;
- Molla, Linda;
- Baker, Lisa;
- Marangoni, M. Natalia;
- Berth, Sarah;
- Tavassoli, Ehsan;
- Bagnato, Carolina;
- Tiwari, Ashutosh;
- Hayward, Lawrence J.;
- Pigino, Gustavo F.;
- Watterson, D. Martin;
- Huang, Chun-Fang;
- Banker, Gary;
- Brown Jr, Robert H.;
- Brady, Scott T.
Publication type:
Article
Homologous Recombination Mediates Functional Recovery of Dysferlin Deficiency following AAV5 Gene Transfer.
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039233
By:
- Grose, William E.;
- Reed Clark, K.;
- Griffin, Danielle;
- Malik, Vinod;
- Shontz, Kimberly M.;
- Montgomery, Chrystal L.;
- Lewis, Sarah;
- Brown, Jr., Robert H.;
- Janssen, Paul M. L.;
- Mendell, Jerry R.;
- Rodino-Klapac, Louise R.
Publication type:
Article
Effect of Parenchymal Stiffness on Canine Airway Size with Lung Inflation.
Published in:
PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0010332
By:
- Brown, Robert H.;
- Kaczka, David W.;
- Mitzner, Wayne
Publication type:
Article
The Role of Copy Number Variation in Susceptibility to Amyotrophic Lateral Sclerosis: Genome-Wide Association Study and Comparison with Published Loci.
Published in:
PLoS ONE, 2009, v. 4, n. 12, p. 1, doi. 10.1371/journal.pone.0008175
By:
- Wain, Louise V.;
- Pedroso, Inti;
- Landers, John E.;
- Breen, Gerome;
- Shaw, Christopher E.;
- Nigel Leigh, P.;
- Brown, Robert H.;
- Tobin, Martin D.;
- Al-Chalabi, Ammar
Publication type:
Article
Natural history and biomarkers in hereditary sensory neuropathy type 1.
Published in:
Muscle & Nerve, 2015, v. 51, n. 4, p. 489, doi. 10.1002/mus.24336
By:
- Fridman, Vera;
- Oaklander, Anne louise;
- David, William S.;
- Johnson, Elise A.;
- Pan, Jessica;
- Novak, Peter;
- Brown, Robert H.;
- Eichler, Florian S.
Publication type:
Article
Arimoclomol at dosages up to 300 mg/day is well tolerated and safe in amyotrophic lateral sclerosis.
Published in:
Muscle & Nerve, 2008, v. 38, n. 1, p. 837, doi. 10.1002/mus.21059
By:
- Cudkowicz, Merit E.;
- Shefner, Jeremy M.;
- Simpson, Elizabeth;
- Grasso, Daniela;
- Yu, Hong;
- Zhang, Hui;
- Shui, Amy;
- Schoenfeld, David;
- Brown, Robert H.;
- Wieland, Scott;
- Barber, Jack R.
Publication type:
Article
Clinical Trial of Losartan for Pulmonary Emphysema: Pulmonary Trials Cooperative Losartan Effects on Emphysema Progression Clinical Trial.
Published in:
2022
By:
- Wise, Robert A.;
- Holbrook, Janet T.;
- Brown, Robert H.;
- Criner, Gerard J.;
- Dransfield, Mark T.;
- Jiaxian He;
- Henderson, Robert J.;
- Kaminsky, David A.;
- Kaner, Robert J.;
- Lazarus, Stephen C.;
- Make, Barry J.;
- McCormack, Meredith C.;
- Neptune, Enid R.;
- Que, Loretta G.;
- He, Jiaxian
Publication type:
journal article
Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways.
Published in:
2015
By:
- Brown, Robert H.;
- Reynolds, Curt;
- Brooker, Allison;
- Talalay, Paul;
- Fahey, Jed W.
Publication type:
journal article
Saving primary care.
Published in:
British Columbia Medical Journal, 2023, v. 65, n. 9, p. 327
By:
- Brown, Robert H.
Publication type:
Article
Value of family physicians.
Published in:
British Columbia Medical Journal, 2021, v. 63, n. 5, p. 198
By:
- Brown, Robert H.
Publication type:
Article
Corporatization of family medicine in BC.
Published in:
British Columbia Medical Journal, 2020, v. 82, n. 5, p. 163
By:
- Brown, Robert H.
Publication type:
Article
Chaos in primary care.
Published in:
British Columbia Medical Journal, 2020, v. 62, n. 1, p. 8
By:
- Brown, Robert H.
Publication type:
Article
The medical home.
Published in:
2017
By:
- Brown, Robert H.
Publication type:
Letter to the Editor
Re: Management of influenza with Tamifu.
Published in:
British Columbia Medical Journal, 2016, v. 58, n. 1, p. 7
By:
- Brown, Robert H.
Publication type:
Article
Birth order and the genetics of amyotrophic lateral sclerosis.
Published in:
Journal of Neurology, 2008, v. 255, n. 1, p. 99, doi. 10.1007/s00415-007-0709-2
By:
- Vivekananda, Umesh;
- Johnston, Clare;
- McKenna-Yasek, Diane;
- Shaw, Christopher E.;
- Leigh, P. Nigel;
- Brown, Robert H.;
- Al-Chalabi, Ammar
Publication type:
Article
Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11837-y
By:
- Giampetruzzi, Anthony;
- Danielson, Eric W.;
- Gumina, Valentina;
- Jeon, Maryangel;
- Boopathy, Sivakumar;
- Brown, Robert H.;
- Ratti, Antonia;
- Landers, John E.;
- Fallini, Claudia
Publication type:
Article

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