We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A COMPARATIVE ANALYSIS OF ISOPROPYL ALCOHOL AND ONDANSETRON IN THE TREATMENT OF POSTOPERATIVE NAUSEA AND VOMITING FROM THE HOSPITAL SETTING TO THE HOME.
- Authors
Cotton, Jonathan W.; Rowell, Lana R.; Hood, Raymond R.; Pellegrini, Joseph E.
- Abstract
We compared the efficacy of inhaled isopropyl alcohol (IPA) with ondansetron for the control of postoperative nausea and vomiting (PONV) during a 24-hour period in 100 ASA class I-Ill women undergoing laparoscopic surgery. Nausea was measured postoperatively using a 0 to 10 verbal numeric rating scale (VNRS). The control group received ondansetron, 4 mg intravenously, and the experimental group inhaled IPA vapors. Breakthrough PONV was treated with 25-mg promethazine suppositories. Demographic and anesthesia characteristics were similar between groups. There was a significant difference between groups in mean ± SD time to alleviation of PONV symptoms: for a 50% reduction in VNRS scores, 15.00 ± 10.6 vs 33.88 ± 23.2 minutes was required in the experimental vs the control group (P = .001). A total of 21 subjects (10 control; 11 experimental) reported PONV symptoms following discharge to home. The IPA treatment was successful in alleviating PONV symptoms in the home in 91% of the experimental group. We determined that using IPA after discharge from the postanesthesia care unit is a valuable method to control PONV in the hospital and at home. The results of this study suggest that IPA is much faster than ondansetron for 50% relief of nausea.
- Subjects
AROMATHERAPY; COMPARATIVE studies; ISOPROPYL alcohol; POSTOPERATIVE nausea &; vomiting; LAPAROSCOPIC surgery; POSTOPERATIVE care
- Publication
AANA Journal, 2007, Vol 75, Issue 1, p21
- ISSN
0094-6354
- Publication type
Article