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- Title
Management of oropharyngeal cancer in Latin America.
- Authors
Costa Diaz, Otávio; Zanella, Virgilio; Janoski de Menezes, Juliana; Lim, Fiona; Wan, Bo Angela; Silva, Maurício F.
- Abstract
Oropharyngeal cancer (OC) represents 0.5% of all cancers in the world. Tobacco and alcohol abuse are major risks factors, and in recent years, we have had an increase in OC related to human papilloma virus (HPV) infection. The prognosis of HPV related tumors is better than smoking related tumors. Early stage tumors can be effectively treated with primary surgery or radiation therapy. Radiation is done with hyperfractionated or accelereted schedules. For advanced stage tumors, the preferred treatment is radiation therapy with concomitant cisplatin and in this case, radiation is done with standard fractionation. Induction chemotherapy fails to show an improvement in overall survival, but is an option in patients with bulky cervical lesions. A multidisciplinary approach is essential in the treatment of this cancer.
- Subjects
LATIN America; CISPLATIN; PAPILLOMAVIRUS diseases; RADIOTHERAPY; TUMOR classification; OROPHARYNGEAL cancer; CHEMORADIOTHERAPY; DISEASE complications
- Publication
Journal of Pain Management, 2019, Vol 12, Issue 3, p197
- ISSN
1939-5914
- Publication type
Article