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- Title
Prognostic nomogram for patients with minor stroke and transient ischaemic attack.
- Authors
Zhihao Lei; Shuanglin Li; Hongye Feng; Yupeng Lai; Yanxia Zhou; Chao Li; Lijie Ren; Lei, Zhihao; Li, Shuanglin; Feng, Hongye; Lai, Yupeng; Zhou, Yanxia; Li, Chao; Ren, Lijie
- Abstract
<bold>Background: </bold>Ischaemic stroke and transient ischaemic attack (TIA) share a common cause. We aim to develop and validate a concise prognostic nomogram for patients with minor stroke and TIA.<bold>Methods: </bold>A total of 994 patients with minor stroke and TIA were included. They were split into a derivation (n=746) and validation (n=248) cohort. The modified Rankin Scale (mRS) scores 3 months after onset were used to assess the prognosis as unfavourable outcome (mRS≥2) or favourable outcome (mRS<2).<bold>Result: </bold>The final model included seven independent predictors: gender, age, baseline National Institute of Health Stroke Scale (NIHSS), hypertension, diabetes mellitus, white blood cell and serum uric acid. The Harrell's concordance index (C-index) of the nomogram for predicting the outcome was 0.775 (95% CI 0.735 to 0.814), which was confirmed by the validation cohort (C-index=0.787 (95% CI 0.722 to 0.853)). The calibration curve showed that the nomogram-based predictions were consistent with actual observation in both derivation cohort and validation cohort.<bold>Conclusion: </bold>The proposed nomogram showed favourable predictive accuracy for minor stroke and TIA. This has the potential to contribute to clinical decision-making.
- Subjects
TRANSIENT ischemic attack; ISCHEMIC stroke; STROKE; NOMOGRAPHY (Mathematics); LEUCOCYTES; STROKE patients; GENDER
- Publication
Postgraduate Medical Journal, 2021, Vol 97, Issue 1152, p644
- ISSN
0032-5473
- Publication type
journal article
- DOI
10.1136/postgradmedj-2020-137680