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- Title
Cholesterol metabolism and Rett syndrome pathogenesis.
- Authors
Nagy, Gabor; Ackerman, Susan L
- Abstract
Rett syndrome is caused by mutations in the gene encoding the transcriptional regulator MECP2. A new study demonstrates that cholesterol homeostasis is disrupted in Mecp2 mutant mice and suggests new therapeutic options for this disease.
- Subjects
RETT syndrome; CHOLESTEROL metabolism; GENETIC mutation; GENETIC code; GENETIC transcription regulation; LABORATORY mice; THERAPEUTICS
- Publication
Nature Genetics, 2013, Vol 45, Issue 9, p965
- ISSN
1061-4036
- Publication type
Article
- DOI
10.1038/ng.2738