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- Title
Diabetes mellitus and other underlying conditions in patients with coronavirus disease 2019 associated rhino-orbito-cerebral mucormycosis: a systematic review and meta-analysis.
- Authors
Zobairy, H; Salem, M M; Ghajarzadeh, M; Mirmosayyeb, O; Mirsalehi, M
- Abstract
Objective: This study aimed to compute the pooled prevalence of diabetes mellitus and other underlying conditions in patients with coronavirus disease 2019 associated rhino-orbito-cerebral mucormycosis. Method: A systematic literature review was performed in PubMed, Scopus, Web of Science, Embase and Google Scholar. The cross-sectional studies that reported the frequency of diabetes mellitus in patients with coronavirus disease 2019 associated rhino-orbito-cerebral mucormycosis were included. Results: Eighteen eligible studies with a total number of 3718 patients were included in the current study. The pooled prevalence of diabetes in patients with coronavirus disease 2019 associated rhino-orbito-cerebral mucormycosis was 89 per cent and with new-onset diabetes was 32 per cent. The pooled prevalence of steroid use was high (79 per cent) too. The all-cause mortality rate was 24 per cent. Conclusion: Diabetes mellitus was the most frequent underlying condition in patients with coronavirus disease 2019 associated rhino-orbito-cerebral mucormycosis. The second most frequent underlying condition was steroid use during coronavirus disease 2019 infection. The appropriate control of hyperglycaemia and rational prescription of steroids during the treatment of coronavirus disease 2019 associated rhino-orbito-cerebral mucormycosis is recommended.
- Subjects
ONLINE information services; CAUSES of death; COVID-19; BRAIN diseases; META-analysis; MEDICAL information storage &; retrieval systems; SYSTEMATIC reviews; STEROIDS; PARANASAL sinus diseases; DIABETES; ZYGOMYCOSIS; MYCOSES; EYE infections; DISEASE prevalence; DESCRIPTIVE statistics; NOSE diseases; MEDLINE; ORBITAL diseases
- Publication
Journal of Laryngology & Otology, 2022, Vol 136, Issue 9, p788
- ISSN
0022-2151
- Publication type
Article
- DOI
10.1017/S0022215122001074