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- Title
Common carotid artery intima-media thickness is useful for diagnosis of the acute stage of Kawasaki disease.
- Authors
Wu, Ting-Hsin; Kuo, Hsuan-Chang; Tain, You-Lin; Lin, Kuan-Miao; Kuo, Ho-Chang; Chien, Shao-Ju
- Abstract
<bold>Background: </bold>This study aimed to investigate intima-media thickness (IMT) of the common carotid arteries in children with acute Kawasaki disease (KD).<bold>Methods: </bold>Between 2009 and 2011, patients fulfilling the criteria for KD, including a fever lasting >5 days, were prospectively enrolled in this study. Laboratory data, echocardiography, and IMT were measured and compared with matched controls.<bold>Results: </bold>A total of 70 common carotid IMTs were measured in 35 children. We studied 21 patients aged 3-60 months old with acute KD and 14 febrile patients aged 3-194 months old with acute infection and similar characteristics to those of KD patients. Children with KD had a significantly higher IMT compared with the controls (0.550 ± 0.081 mm vs. 0.483 ± 0.046 mm, P = 0.01).<bold>Conclusions: </bold>IMT during the acute stage of KD is increased, suggesting that IMT could be a useful diagnostic tool in the early diagnosis of KD.
- Subjects
BLOOD pressure; CAROTID artery; ECHOCARDIOGRAPHY; FEVER; MUCOCUTANEOUS lymph node syndrome; CAROTID intima-media thickness
- Publication
BMC Pediatrics, 2014, Vol 14, Issue 1, p98
- ISSN
1471-2431
- Publication type
journal article
- DOI
10.1186/1471-2431-14-98