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Defects of mutant DNMT1 are linked to a spectrum of neurological disorders.
Published in:
Brain: A Journal of Neurology, 2015, v. 138, n. 4, p. 845, doi. 10.1093/brain/awv010
By:
- Baets, Jonathan;
- Xiaohui Duan;
- Yanhong Wu;
- Smith, Gordon;
- Seeley, William W.;
- Mademan, Inès;
- McGrath, Nicole M.;
- Beadell, Noah C.;
- Khoury, Julie;
- Botuyan, Maria-Victoria;
- Mer, Georges;
- Worrell, Gregory A.;
- Hojo, Kaori;
- DeLeon, Jessica;
- Laura, Matilde;
- Yo-Tsen Liu;
- Senderek, Jan;
- Weis, Joachim;
- Van den Bergh, Peter;
- Merrill, Shana L.
Publication type:
Article
SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26049-6
By:
- Ma, Jian;
- Shi, Qing;
- Cui, Gaofeng;
- Sheng, Haoyue;
- Botuyan, Maria Victoria;
- Zhou, Yingke;
- Yan, Yuqian;
- He, Yundong;
- Wang, Liguo;
- Wang, Yuzhuo;
- Mer, Georges;
- Ye, Dingwei;
- Wang, Chenji;
- Huang, Haojie
Publication type:
Article
Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss.
Published in:
Nature Genetics, 2011, v. 43, n. 6, p. 595, doi. 10.1038/ng.830
By:
- Klein, Christopher J.;
- Botuyan, Maria-Victoria;
- Yanhong Wu;
- Ward, Christopher J.;
- Nicholson, Garth A.;
- Hammans, Simon;
- Hojo, Kaori;
- Yamanishi, Hiromitch;
- Karpf, Adam R.;
- Wallace, Douglas C.;
- Simon, Mariella;
- Lander, Cecilie;
- Boardman, Lisa A.;
- Cunningham, Julie M.;
- Smith, Glenn E.;
- Litchy, William J.;
- Boes, Benjamin;
- Atkinson, Elizabeth J.;
- Middha, Sumit;
- Dyck, P. James B.
Publication type:
Article
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination.
Published in:
Nature Structural & Molecular Biology, 2013, v. 20, n. 3, p. 317, doi. 10.1038/nsmb.2499
By:
- Tang, Jiangbo;
- Cho, Nam Woo;
- Cui, Gaofeng;
- Manion, Erica M;
- Shanbhag, Niraj M;
- Botuyan, Maria Victoria;
- Mer, Georges;
- Greenberg, Roger A
Publication type:
Article
PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.
Published in:
Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 916, doi. 10.1038/nsmb.2353
By:
- Cui, Gaofeng;
- Park, Sungman;
- Badeaux, Aimee I;
- Kim, Donghwa;
- Lee, Joseph;
- Thompson, James R;
- Yan, Fei;
- Kaneko, Satoshi;
- Yuan, Zengqiang;
- Botuyan, Maria Victoria;
- Bedford, Mark T;
- Cheng, Jin Q;
- Mer, Georges
Publication type:
Article
Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Published in:
Nature Structural & Molecular Biology, 2008, v. 15, n. 1, p. 109, doi. 10.1038/nsmb1326
By:
- Lee, Joseph;
- Thompson, James R.;
- Botuyan, Maria Victoria;
- Mer, Georges
Publication type:
Article
Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46207-w
By:
- Palani, Sowmiya;
- Machida, Yuka;
- Alvey, Julia R.;
- Mishra, Vandana;
- Welter, Allison L.;
- Cui, Gaofeng;
- Bragantini, Benoît;
- Botuyan, Maria Victoria;
- Cong, Anh T. Q.;
- Mer, Georges;
- Schellenberg, Matthew J.;
- Machida, Yuichi J.
Publication type:
Article
An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41821-6
By:
- Cui, Gaofeng;
- Botuyan, Maria Victoria;
- Drané, Pascal;
- Hu, Qi;
- Bragantini, Benoît;
- Thompson, James R.;
- Schuller, David J.;
- Detappe, Alexandre;
- Perfetti, Michael T.;
- James, Lindsey I.;
- Frye, Stephen V.;
- Chowdhury, Dipanjan;
- Mer, Georges
Publication type:
Article
Letter to the Editor: 1H, 13C and 15N Assignments of Single-Stranded DNA Binding Domains from the 70 kDa Subunit of Human Replication Protein A.
Published in:
Journal of Biomolecular NMR, 2004, v. 28, n. 2, p. 195, doi. 10.1023/B:JNMR.0000013818.02364.3a
By:
- Bhattacharya, Shibani;
- Arunkumar, Alphonse I.;
- Sullivan, Shannon L.;
- Botuyan, Maria-Victoria;
- Arrowsmith, Cheryl H.;
- Chazin, Walter J.
Publication type:
Article
Stabilization of Nucleosomes by Histone Tails and by FACT Revealed by spFRET Microscopy.
Published in:
Cancers, 2017, v. 9, n. 1, p. 3, doi. 10.3390/cancers9010003
By:
- Valieva, Maria E.;
- Gerasimova, Nadezhda S.;
- Kudryashova, Kseniya S.;
- Kozlova, Anastasia L.;
- Kirpichnikov, Mikhail P.;
- Qi Hu;
- Botuyan, Maria Victoria;
- Mer, Georges;
- Feofanov, Alexey V.;
- Studitsky, Vasily M.
Publication type:
Article
Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.
Published in:
Nature, 2012, v. 483, n. 7387, p. 104, doi. 10.1038/nature10861
By:
- Su, Dan;
- Hu, Qi;
- Li, Qing;
- Thompson, James R.;
- Cui, Gaofeng;
- Fazly, Ahmed;
- Davies, Brian A.;
- Botuyan, Maria Victoria;
- Zhang, Zhiguo;
- Mer, Georges
Publication type:
Article
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52862-w
By:
- Kilgas, Susan;
- Syed, Aleem;
- Toolan-Kerr, Patrick;
- Swift, Michelle L.;
- Roychoudhury, Shrabasti;
- Sarkar, Aniruddha;
- Wilkins, Sarah;
- Quigley, Mikayla;
- Poetsch, Anna R.;
- Botuyan, Maria Victoria;
- Cui, Gaofeng;
- Mer, Georges;
- Ule, Jernej;
- Drané, Pascal;
- Chowdhury, Dipanjan
Publication type:
Article
Characterization of binding-induced changes in dynamics suggests a model for sequence-nonspecific binding of ssDNA by replication protein A.
Published in:
Protein Science: A Publication of the Protein Society, 2002, v. 11, n. 10, p. 2316, doi. 10.1110/ps.0209202
By:
- Bhattacharya, Shibani;
- Botuyan, Maria-Victoria;
- Hsu, Fred;
- Shan, Xi;
- Arunkumar, A.I.;
- Arrowsmith, Cheryl H.;
- Edwards, Aled M.;
- Chazin, Walter J.
Publication type:
Article

Found: 13

Defects of mutant DNMT1 are linked to a spectrum of neurological disorders.

SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition.

Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss.

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination.

PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.

Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.

Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes.

An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering.

Letter to the Editor: <sup>1</sup>H, <sup>13</sup>C and <sup>15</sup>N Assignments of Single-Stranded DNA Binding Domains from the 70 kDa Subunit of Human Replication Protein A.

Stabilization of Nucleosomes by Histone Tails and by FACT Revealed by spFRET Microscopy.

Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106.

NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity.

Characterization of binding-induced changes in dynamics suggests a model for sequence-nonspecific binding of ssDNA by replication protein A.