We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Effect of Cibenzoline on Biventricular Pressure Gradients in a Pediatric Patient with Hypertrophic Obstructive Cardiomyopathy.
- Authors
Ishikawa, Takamichi; Iwashima, Satoru; Ohzeki, Takehiko
- Abstract
This report presents the case of an 8-year-old male with biventricular hypertrophic obstructive cardiomyopathy who achieved a successful reduction of the pressure gradients by treatment with cibenzoline. Ultrasound echocardiography showed marked intraventricular septal hypertrophy and left midventricular and right ventricular outflow obstructions. A cardiac catheterization revealed left midventricular and right outflow obstructions associated with pressure gradients of 100 and 35 mmHg, respectively. An intravenous injection of 28 mg (1.4 mg/kg) cibenzoline immediately improved the biventricular pressure gradients. Therefore, oral cibenzoline treatment was initiated, the dose was increased to 150 mg/day, and both pressure gradients remained low, without any complications at the time of discharge, 4 months later.
- Subjects
CASE studies; HYPERTROPHIC cardiomyopathy; PEDIATRIC therapy; ECHOCARDIOGRAPHY; MEDICAL imaging systems
- Publication
Pediatric Cardiology, 2010, Vol 31, Issue 5, p707
- ISSN
0172-0643
- Publication type
Article
- DOI
10.1007/s00246-010-9651-7