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- Title
Evidence of bluetongue virus serotype 21 (BTV-21) divergence.
- Authors
Susmitha, B.; Sudheer, D.; Rao, Pavuluri; Uma, Madala; Prasad, Gaya; Minakshi, P.; Hegde, Nagendra; Reddy, Y.
- Abstract
Bluetongue virus serotype 21 (BTV-21) was originally isolated from Australia, but has now been reported from India, Indonesia, China and Japan. We report the isolation, and sequencing of BTV-21 from India. The complete ORF sequence of VP2 gene of this isolate showed that it is closely related to recent BTV-21 isolates from Japan (93-94% identity), and distantly related to BTV-21 reference strain (86% identity). Our results, along with the available sequences of Japanese isolates, suggest that the currently circulating BTV-21 strains from India and Japan are divergent from the original strain(s) from Australia and shed light on designing molecular diagnostics for the detection of BTV.
- Subjects
AUSTRALIA; INDIA; JAPAN; BLUETONGUE virus; GENES; MOLECULAR diagnosis
- Publication
Virus Genes, 2012, Vol 44, Issue 3, p466
- ISSN
0920-8569
- Publication type
Article
- DOI
10.1007/s11262-012-0724-y